Searchable abstracts of presentations at key conferences on calcified tissues
Bone Abstracts (2013) 2 P9 | DOI: 10.1530/boneabs.2.P9

ICCBH2013 Poster Presentations (1) (201 abstracts)

A 6-month intervention study with vibration therapy in severely disabled children: effects on bone, biochemical markers and acceptance

Diana Swolin-Eide 1 , Gunnar Braathen 2 , Roger Emilsson 2 , Ulla Glansen 2 , Ann-Charlott Söderpalm 3 , Per Magnusson 4 , Bosse Zetterlund 2 , Barbro Westerberg 2 & Sophie Kilebrant 2


1Department of Paediatrics, Institute of Clinical Sciences, The Queen Silvia Children’s Hospital, Gothenburg, Sweden; 2Habilitation and Health, Västra Götalandregionen, Child and Youth Habilitation, Gothenburg, Sweden; 3Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; 4Division of Clinical Chemistry, Linköping University, Linköping, Sweden.


Objectives: To study acceptance and the effects on bone during a 6-month whole body vibration (WBV) therapy in severely disabled children.

Methods: Nineteen patients, age 5–16 years, with severe motor disabilities completed the 6-month WBV therapy standing on a self-controlled dynamic platform with vibration, jumps and rotation. The WBV was performed twice per week at 40–42 Hz. Bone mass and biochemical markers were measured at start and after 6 and 12 months.

Results: WBV was perceived as positive by children and staff. Fractures were reported during the study and 58% of the children had sustained fractures earlier in life. Total body bone mineral density (BMD) (head excluded) and total body bone mineral content (BMC) (head excluded), increased over the study period (P<0.05). Total body BMD Z-scores were low in the group (range −4.4 to −0.8) at start and did not change. Their BMI, fat and lean mass were unchanged during the WBV. Markers of bone and mineral metabolism did not change significantly, except for a small decrease in serum calcium. CTX, a marker of bone resorption, was increased in 8 of 19 patients. Some patients normalized their CTX levels after WBV, which could indicate a positive response to WBV. However, the actual CTX values did not change significantly.

Conclusion: WBV appears to be safe and well-tolerated. Total body BMD and BMC (head excluded) increased; however, the Z-scores were low and unchanged over the study period. The low BMD Z-scores could be an effect of increased bone resorption and decreased bone formation. Larger study groups, and possibly longer vibration treatment periods, are needed to elucidate the potential benefits of WBV on bone mass in children with severe motor disabilities.

Volume 2

6th International Conference on Children's Bone Health

Rotterdam, The Netherlands
22 Jun 2013 - 25 Jun 2013

ICCBH 

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