Searchable abstracts of presentations at key conferences on calcified tissues
Bone Abstracts (2014) 3 PP261 | DOI: 10.1530/boneabs.3.PP261

ECTS2014 Poster Presentations Osteoporosis: pathophysiology and epidemiology (38 abstracts)

The relationship between pulmonary function and bone mineral density in healthy non-smoking women: The Korean National Health and Nutrition Examination Survey (KNHANES) 2010

Yun Kyung Jeon 1 , Myung Jun Shin 2 , Seong Jang Kim 3 , In Joo Kim 1 , Bo Hyun Kim 1 & Sang Soo Kim 1


1Division of Endocrinology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Republic of Korea; 2Department of Rehabilitation Medicine, Pusan National University Hospital, Busan, Republic of Korea; 3Department of Nuclear medicin, Pusan National University Hospital, Busan, Republic of Korea.


Introduction: It has been reported that low bone mass is common in patients with pulmonary disorders such as chronic obstructive pulmonary disease. However, in healthy non-smoking women, the relationship between bone mass and pulmonary function has yet to be clarified. The object of this study was to determine whether pulmonary function is related to BMD in healthy non-smoking women based on menopausal status.

Methods: This study was a cross-sectional study based on data obtained from the Korean National Health and Nutrition Examination Survey (KNHANES), a nation-wide representative survey conducted by the Korean Ministry of Health and Welfare in 2010. This study included 506 subjects who had never smoked and analyzed data concerning pulmonary function and BMD.

Results: Functional vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) were correlated with BMD at lumbar spine, femur neck (FN), and total hip in premenopausal women (P=0.030, P=0.003, and P=0.019 respectively for FVC; P=0.015, P=0.006, and P=0.059 respectively for FEV1). However, FVC and FEV1 were only correlated with BMD at FN in postmenopausal women (P=0.003 for FVC and P=0.006 for FEV1). BMI, FVC, and FEV1 were significantly related with BMD at FN, even after adjusting for age and other confounding factors (β=0.334, P<0.001, β=0.145, P=0.017, and β=0.129, P=0.037 respectively) in premenopausal women. However, only age and BMI were correlated with BMD at FN (β=−0.268, P=0.001 and β=0.384, P<0.001) in postmenopausal women after adjusting for confounding factors.

Conclusions: Pulmonary function, including FVC and FEV1 are associated with BMD at FN in healthy non-smoking premenopausal women but not in postmenopausal women.

Volume 3

European Calcified Tissue Society Congress 2014

Prague, Czech Republic
17 May 2014 - 20 May 2014

European Calcified Tissue Society 

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