ICCBH2015 Poster Presentations (1) (201 abstracts)
Low serum vitamin D levels in children treated for hematologic oncologic diseases
Daniela Sperl 1 , Tobias Krause 1 , Herwig Lackner 1 , Barbara Obermayer-Pietsch 2 , Clare Decrinis 2 , Astrid Berger 2 , Petra Sovinz 1 , Markus Seidel 1 , Wolfgang Schwinger 1 , Martin Benesch 1 , Volker Strenger 1 , Sandrin Schmidt 1 & Christian E Urban 1
1Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology/Oncology, Medical University of Graz, Graz, Austria; 2Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Objectives: Vitamin D deficiency is of current interest especially in high risk patients for reduced bone mineral density as in pediatric hematologic oncologic patients.
Methods: During a 4 year period 194 pediatric hematologic oncologic patients were screened for serological vitamin D deficiency (defined as 25 (OH)D levels <30 ng/ml and accordingly <75 nmol/l). 61 patients were in the prospective group 1 defined as screening at time of diagnosis, 35 patients were in the group 2 defined as screening at time of follow up <1 year after therapy and 98 patients were in group 3 defined as screening at time of follow up >1 year after therapy.
Results: Overall 112/194 patients (57.7%) had vitamin D deficiency, 49/61patients (80%) in group 1, 19/35 patients (54%) in group 2, 44/98 patients (44.8%) in group 3. All patients with proven vitamin D deficiency received an oral supplementation with cholecalciferol.
Conclusion: Screening for serological vitamin D deficiency is important to reduce the risk of reduced bone mineral density especially in patients at high risk as pediatric hematologic oncologic patients.
Disclosure: The authors declared no competing interests.
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