Bone Abstracts

Bone is a dynamic tissue as well as an endocrine organ, with a broad range of functions, such as static balance and locomotion, protection of internal organs, hematopoiesis, mineral storage and hormonal regulation. Bone growth and bone loss and functional changes during lifetime are important factors for human health.

Metabolic bone diseases may occur in many circumstances via a disturbed balance of the complex cellular interactions involved in bone microarchitecture and function. Osteoporosis and osteomalacia, chronic kidney disease with consecutive metabolic bone disease (CKD-MBD) or bone changes during primary hyperparathyroidism or diabetes underline the interaction of organ systems with bone in health and disease. Bone fractures and fracture healing are important topics to discover. We are going to understand more and more of the molecular mechanisms and the metabolic regulation behind these processes.

Thus, specific diagnostic and therapeutic tools have been established and more research is on the way. Therefore, the knowledge of systemic conditions and diseases, including the nutritional influences are important factors in the interpretation and prevention of detrimental influences on bone health and on human health in general.