The purpose of this study is to assess the correlation of trabecular bone score (TBS) to variable factors, i.e. sex, age, body size and BMD. Moreover, we want to find variables of correlation coefficient change with aging.
We randomly selected 2,906 subjects (1726 female and 1180 male, age range 20s to 70s) from several hospitals in Korea. Participants who have abnormal Dual Energy X-ray Absorptiometry (DXA) images or lumbar disease were excluded. TBSiNsight software (v. 2.1.1, Med-Imaps, Boedeaux, France) was used to calculate the TBS score as well as BMD values from DXA images. Statistical analysis was performed using correlation analysis. Among female participants, we have compared TBS and BMD values of those who are older than 65 years with all age group.
The correlation coefficient of TBS and BMD was the highest in 30s and gradually decreased with aging. Correlation coefficients between TBS and age (R=−0.68), height (R=0.54), LS-BMD (R=0.72) in all female participant were significantly higher than male but R values were decreased in the age group above 65.
In this study, TBS showed a strong correlation with age, BMD in both gender. However, TBS showed a significant correlation with height in female participants only. TBS and BMD showed high correlation but gradually decreased with aging. Therefore, we believe TBS and BMD have different mechanism of accessing bone quality in aged group. In conclusion, TBS should be used together with BMD for osteoporosis diagnosis especially in elderly.
14 - 17 May 2016
European Calcified Tissue Society