Bone Abstracts

Although the baby growing in its mother’s womb needs calcium for skeletal development osteoporosis and fractures very rarely occur during pregnancy. Pregnancy- and lactation-associated osteoporosis with the occurrence of fragility fractures mainly of the vertebral bodies was first described as a syndrome Nordin et al. in 1955. It is most commonly observed in the third trimester or early post-partum in women presenting with severe and prolonged back pain and somet...

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Vertebral fractures (VFX) are the most prevalent fracture associated with osteoporosis and often cause severe pain which can become chronic. VFX are associated with a high risk of further fracture, increased mortality, and reduced quality of life. Vertebroplasty and kyphoplasty are techniques involving the percutaneous injection of bone cement into one or more symptomatic fractured vertebrae. In vertebroplasty, cement is injected directly into the bone, while in kyphoplasty, c...

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Oftenly, the question arises whether anti-osteoporotic drugs should be prescribed in glucocorticoid-treated premenopausal women. On the one hand, there are strong arguments to prescribe these drugs, when these patients are treated with high dose glucocorticoïds, and suffer from diseases that have a negative effect on bone, for instance SLE.On the other hand, the absolute fracture risk is low, related to their young age, and finally, in women with ch...