Bone Abstracts

Juvenile dermatomyositis (JDM) is a severe connective-tissue disease of unknown etiology characterized by inflammatory process affecting muscles and skin, with subsequent presentation in the joints, esophagus, lungs, and the cardiovascular system. Clinical presentation also includes deposition of calcium in the skin (calcinosis cutis) which is typically seen in the juvenile DM, contrary to the adult form. The pathogenesis of JDM-related calcinosis remains unclear wher...

Vitamin D deficiency has been reported in adult patients with autoimmune diseases including rheumatoid arthritis, however, the data in patients with juvenile idiopathic arthritis (JIA) are inconsistent. The aim of the study was to assess serum 25-hydroxyvitamin D (25(OH) D in children and adolescents with JIA, and to determine potential risk factors for vitamin D deficiency.In this cross-sectional study, we evaluated 189 patients with JIA (113 girls, 76 ...