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Bone Abstracts (2013) 1 PP94 | DOI: 10.1530/boneabs.1.PP94

Ukrainian Medical Stomatological Academy, Poltava, Ukraine.


Damages of bones of facial skeleton lay down 8% from all damages, fractures of mandible are 85–90% from it. There are a lot of factors, that make worse the process of reparative regeneration of bone. Using of nitric fertilizers lead to heighten earning of nitric oxide into organism. It makes negative influence on reparative regeneration of bones.

There are dates of research of 40 rats line Vistar in this article. The goal of this study was to examine the effect of chronic nitric intoxication on the healing of fractures of mandible in different terms after trauma. The fracture of mandible was molded at rats after 60 days of nitric intoxication and without it. Histological investigations of callus were carried out on 14-th, 21-th, 28-th and 35-th days after molded of fracture.

The chronic nitric intoxication slows down the course of regenerator processes of experimental fracture of mandible. It is characterized by slower dynamic of differentiation of cellular elements and micro vessels even at later terms of reparative osteogenesis and delay of forming of trabeculars of bone.

Volume 1

European Calcified Tissue Society Congress 2013

Lisbon, Portugal
18 May 2013 - 22 May 2013

European Calcified Tissue Society 

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