Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp428 | Osteoporosis: treatment | ECTS2013

Persistence with different anti-osteoporosis medications: a population-based cohort study.

Pages-Castella Aina , Carbonell-Abella Cristina , Nogues Xavier , Javaid M Kassim , Arden Nigel K , Cooper Cirus , Diez-Perez Adolfo , Prieto-Alhambra Daniel

Objective: Several reports suggest very low persistence with oral bisphosphonates, but there is a scarcity of data on persistence with other anti-osteoporosis medications. We therefore compared rates of early discontinuation (in the first year of therapy) between all available outpatient anti-osteoporosis drugs in Catalonia, Spain.Study design: population-based retrospective cohort study.Participants and source of data: The data in...

ba0003pp360 | Osteoporosis: treatment | ECTS2014

Predictors of second fracture while on treatment with oral bisphosphonates: a multinational retrospective cohort study

Hawley Sam , Wallace Gemma , Javaid M Kassim , Rubin Katrine , Judge Andrew , Vestergaard Peter , Eastell Richard , Diez-Perez Adolfo , Arden Nigel K , Cooper Cyrus , Prieto-Alhambra Daniel , Abrahamsen Bo

Objective: To identify predictors of inadequate response to oral bisphosphonate therapy, defined as the incidence of ≧2 fractures while on treatment among incident oral bisphosphonate users with high refill compliance (≧80%).Material and methods: Data from computerized records and pharmacy invoices were obtained from SIDIAP (Catalonia, E) and Danish Health Registries (DK) for all incident users of oral bisphosphonates in 2006–2007 and 2000&#15...

ba0005ht4 | (1) | ECTS2016

Vitamin D supplementation in pregnancy leads to greater bone mass in UK infants born during winter months: the MAVIDOS multicentre, randomised, double-blind, placebo-controlled trial

Cooper Cyrus , Harvey Nicholas , Bishop Nicholas , Kennedy Stephen , Papageorghiou Aris , Schoenmakers Inez , Fraser Robert , Gandhi Saurabh , D'Angelo Stefania , Crozier Sarah , Moon Rebecca , Arden Nigel , Dennison Elaine , Godfrey Keith , Inskip Hazel , Prentice Ann , Mughal Zulf , Eastell Richard , Reid David , Javaid Kassim

Maternal vitamin D status has been positively associated with infant bone mass in observational studies. We therefore evaluated whether 1000 IU/day cholecalciferol during pregnancy would lead to greater offspring bone mass at birth, in a UK, multicentre, randomised, double-blind, placebo-controlled trial (MAVIDOS, ISRCTN82927713).At 12 weeks’ gestation, pregnant women with a serum 25-hydroxyvitamin D [25(OH)D] 25-100 nmol/l were randomised to either...