ba0003oc1.1 | Phosphate metabolism, fracture repair and osteoarthritis | ECTS2014
, Borjesson Anna E
, Salter Donald M
, Ralston Stuart H
Background: Cannabinoid receptors are expressed in synovial joints but their role in joint disease is unknown. Here we examined the role of the type 2 cannabinoid receptor (CB2) in the pathogenesis of age-related osteoarthritis and osteoarthritis caused by destabilisation of the medial meniscus (DMM) in WT and CB2-deficient mice (Cnr2−/− mice).Methods: The severity of arthritis was graded histologically according to standard techni...