Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p5 | Arthritis and other joint diseases: translational and clinical | ECTS2016

The effects of hydroxychloroquine on bone turnover

Both T , van der Eerden B C J , Koedam M , Zillikens M C , van Laar J A M , Dalm V A S H , van Leeuwen H P T M , van Hagen P M , van Daele P L A

Introduction: We recently showed that patients with primary Sjögren Syndrome (pSS) have significantly higher bone mineral density (BMD) in the lumbar spine and femoral neck compared with healthy controls. The majority of those patients (69%) were using hydroxychloroquine (HCQ), which may have favourable effects on BMD.Aim: To evaluate whether HCQ modulates human bone cells in vitro.Methods: Osteoblasts were differenti...