Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp188 | Genetics | ECTS2014

Correlation of miRNA-mRNA regulatory network profile with bone mass in inbred strains of mice

Shin Chansoo , An Jee Hyun , Song Jung A , Yang Jae-Yeon , Choi Hyung Jin , Kim Sang Wan

Growing body of evidence shows that microRNAs play an important role in regulating bone mass. We investigated the cooperative microRNA-mRNA regulatory mechanism of peak bone mass in inbred strain of mice with different bone density using microarray analysis. Femur and tibia of 12-week old C3H/He (high bone density) and C57BL/6 (low bone density) were harvested to extract total bone RNAs for microarray. A total of 30 miRNAs were differentially expressed between bone tissue of C...

ba0005p368 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Gender-different relationship between body composition and incident fracture risk in Koreans: a community-dwelling prospective cohort study

Kim Jung Hee , Hong A Ram , Choi Hyung Jin , Ku Eu Jeong , Cho Nam H , Shin Chan Soo

Low body mass index (BMI) or body weight is a well-known risk factor for osteoporosis and fragility fractures. However, the relative contribution of lean mass and fat mass on bone health, i.e. fragility fractures is inconclusive.We elucidated the relative contribution of lean and fat mass on fracture risk by group analysis in Korean men and women. This was an ongoing prospective community-dwelling cohort study at Ansung in Korea, begun in 2001. We includ...