Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p140 | Cell biology: osteoblasts and bone formation | ECTS2016

Matrix metalloproteinases and their inhibitors (TIMPs and RECK): induction of osteoblastic differentiation modulates their protein levels on mineralization onset in human dental pulp stem cells

Paiva Katiucia , Gasparoni Leticia , Bronzeri Cristiane

Constant remodeling of extracellular matrix is a hallmark during physiological conditions, such as stem cell differentiation, embryogenesis and tissue repair. Matrix metalloproteinases (MMPs) play a key role in these processes. MMPs and MMP-inhibitors (TIMPs) are responsible for bone formation and bone matrix remodeling and, probably, determinate the level of its turnover. Mesenchymal stem cells derived from dental pulp are multipotent and have the capacity to differentiate, a...