Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p369 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Osteoporosis-related knowledge and health beliefs among female community leaders in Peru

Sava Mihaela , Hsieh Evelyn , Garcia Patricia , Mabey David

Background: Postmenopausal women are at high risk for osteoporosis, and early adoption of osteoporosis-preventative behaviours, such as physical activity and dietary calcium intake, can help mitigate this risk. Behavioural studies have shown that knowledge and health beliefs are key factors associated with adoption of healthy behaviours. There are few such studies regarding osteoporosis in South America. Our aim was to conduct an exploratory study evaluating osteoporosis-relat...

ba0005p337 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz therapy among HIV-infected individuals

Hsieh Evelyn , Fraenkel Liana , Han Yang , Xia Weibo , Insogna Karl , Yin Michael , Zhu Ting , Cheng Xinqi , Li Taisheng

Tenofovir disoproxil fumarate (TDF) is a critical component of first-line antiretroviral regimens for HIV worldwide. However, TDF-containing regimens have been associated with decreased bone mineral density and increased fracture risk, which may in part be mediated through secondary elevations in parathyroid hormone (PTH). Prior cross-sectional data suggest vitamin D binding protein (DBP) levels may increase with TDF exposure leading to a functional vitamin D deficiency, which...

ba0005p129 | Cancer and bone: basic, translational and clinical | ECTS2016

Vertebral fractures among breast cancer survivors in China

Hsieh Evelyn , Wang Qin , Zhang Renzhi , Niu Xin , Li Jing , Zhou Chunwu , Qiao Youlin , Xia Weibo , Fraenkel Liana , Insogna Karl , Smith Jennifer , Zhang Pin

Background: Women with breast cancer (BC) are at high risk for fracture due to the deleterious impact of BC therapies on bone. In China, BC survival is improving as screening and treatment programs expand, however no guidelines exist to prevent BC treatment-induced bone loss. We sought to evaluate the scope of this problem among BC survivors receiving care at a large cancer referral hospital in China.Methods: Women were invited to participate in this cro...