Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p254 | Genetics and Epigenetics | ECTS2016

Genetic risk factors for knee osteoarthritis in postmenopausal ukrainian women

Grygorieva Nataliia , Povoroznyuk Vladyslav , Kaliada Aleksander , Krochak Svyatoslava , Balatska Nataliya

Osteoarthritis is a complex pathogenesis because diverse factors interact causing a process of deterioration of the cartilage and the subchondral bone. Despite the multifactorial nature of the knee osteoarthritis, it is related to a strong genetic component. Determination of molecular genetic causes of osteoarthritis is an actual problem. There are several approaches to assess the contribution of a candidate gene in the pathogenesis of osteoarthritis. The aim of the study was ...