Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp147 | Cell biology: osteoblasts and bone formation | ECTS2014

Differential gene expression of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are modulated during osteogenic/odontogenic differentiation from human dental pulp stem cells (DPSCs) by BMP-7

Paiva Katiucia , Silva Luiz , Sogayar Mari , Labriola Leticia

Constant remodeling of extracellular matrix is a hallmark during physiological conditions, such as stem cell differentiation, embryogenesis and tissue repair. Matrix metalloproteinases (MMP) play a key role in these processes. Mesenchymal stem cells derived from dental pulp are multipotent and have the capacity to differentiate into mesenchymal lineages. Bone morphogenetic proteins (BMP) are a family of signaling molecules critically involved at various stages in the formation...