Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p246 | Genetics and Epigenetics | ECTS2016

In a population based association study: IAPP gene variants are not associated with bone phenotypes in elderly women

Mitchell Adam , Grabowski Peter , Luthman Holger , Akesson Kristina , McGuigan Fiona

Skeletal strength, maintained through bone remodelling, is regulated through complex communication networks between bone cells and other tissues including endocrine cells. Bone also functions as an endocrine organ in its own right. The peptide hormone amylin (or Islet Amyloid Polypeptide (IAPP)), has links to both bone and energy metabolism. A member of the calcitonin family of peptides, it is co-secreted with insulin from pancreatic β-cells and is linked with diabetes-as...