ba0001pp32 | Bone biomechanics and quality | ECTS2013
O'Loughlin Peter
, Lee Alice
, Anderson Paul
, Steck Roland
, Forwood Mark
, Sawyer Rebecca
, Morris Howard
We have reported femoral osteopenia in short term-vitamin D restricted rats without deterioration in tibial cortical bone volume (CBV), geometry or strength1. This study aimed to establish the effect of extended vitamin D deficiency in aged rat tibial volume and strength. Female Sprague-Dawley rats (9 m, n=6/group) were fed a diet containing varying vitamin D3 (D) levels (0, 2, 12, and 20 IU/day) with either low (0.1%, LCa) or high (1%, HCa) diet...