ba0001pp173 | Cell biology: osteoblasts and bone formation | ECTS2013
, Omelon Sidney
, Wazen Rima
, Variola Fabio
, Nanci Antonio
Polyphosphates (polyPs) are inorganic phosphate chains found in many cell types with higher concentrations in bone cells. As a source of inorganic phosphate (Pi) and an effective calcium reservoir due to chelation, PolyPs enable total Ca2+ and PO42− concentrations above those required for apatite saturation. Alkaline phosphatase (ALP) cleaves Pi from polyP, thus polyPs may be involved in apatite mineralization.Aim: ...