Searchable abstracts of presentations at key conferences on calcified tissues

ba0002oc2 | Epidemiology | ICCBH2013

Fracture patterns and bone mass in South African adolescent–mother pairs: the Birth to Twenty Cohort

Thandrayen Kebashni , Norris Shane , Micklesfield Lisa , Pettifor John

Differences in fracture rates and bone mass in families and individuals of different ethnic origins may be due to differing lifestyles and/or genetic backgrounds. This study aimed to assess the associations of bone mass and fracture prevalence in adolescents with maternal bone mass and fracture history, and sibling fracture history.Data from 1389 adolescent-biological mother pairs from the Birth to Twenty (Bt20) longitudinal study were obtained. Question...

ba0004p47 | (1) | ICCBH2015

Ethnic and gender differences in metacarpal dimensions in black and white South African children from pre-puberty through adolescence

Magan Ansuyah , Micklesfield Lisa , Norris Shane , Pettifor John

Bone accrual and the attainment of peak bone mass influence an individual’s predisposition to fracture or osteoporosis later in life. The developmental tempo and the movement of the periosteal and endosteal surfaces of the appendicular skeleton during growth result in variations in bone mineral content and density. During puberty the differential in peak height and peak bone mass accretion negatively influence bone strength. A surrogate measure of bone strength is the met...

ba0004p129 | (1) | ICCBH2015

Cortical area and volumetric density during pubertal growth: longitudinal analysis in black and white South African adolescent males

Schoenbuchner Simon , Ward Kate , Norris Shane , Prentice Ann , Pettifor John

Skeletal development during childhood and adolescence is an important determinant of adult bone health. Patterns of growth differ between populations, but it is unclear how these differences relate to changes in bone size and volumetric density. We aimed to examine ethnic differences in skeletal phenotype in the context of pubertal growth and development in 279 adolescent males from Johannesburg, South Africa.We performed annual peripheral quantitative c...

ba0004p188 | (1) | ICCBH2015

Fractures, bone mass and geometry in black and white South African children: The Birth to Twenty cohort

Thandrayen Kebashni , Schoenbuchner Simon , Ward Kate , Micklesfield Lisa , Norris Shane , Prentice Ann , Pettifor John

The prevalence of fractures in white children in South Africa is double that of black children (1). White males who fractured were shown to be more physically (2). The aim of this study was to compare the bone mass and geometry measures using peripheral quantitative computed tomography (pQCT) and dual energy x-ray absorptiometry (DXA) in black and white children with and without a history of fracture to determine the risk factors for fractures.Lifetime f...