Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp252 | Chondrocytes and cartilage | ECTS2013

Modulation of c-Myb during chondrogenesis

Oralova Veronika , Buchtova Marcela , Janeckova Eva , Tucker Abigail , Matalova Eva

The c-Myb transcription factor is associated with proliferation of undifferentiated cells in number of tissues, but recent data suggests its role also in differentiation. c-Myb is important in formation of the cartilage, bone and apparently also in hard tissue mineralization (Matalova et al. 2011).Embryonic micromasses were established from mouse front limbs at the embryonic day E12. Micromass cultures represent an effective tool for experimenta...

ba0003pp61 | Bone development/growth and fracture repair | ECTS2014

Fas ligand in formation of hard tissues

Svandova Eva , Lesot Herve , Oralova Veronika , Poliard Anne , LeDenmat Dominique , Matalova Eva

Among activation of apoptotic machinery, Fas (CD95)/FasL (CD178) were suggested to act in cell proliferation and differentiation. Expression of Fas and FasL was reported during tooth and bone formation. The examination of gld mice showed increased total body bone mass and number of osteoblasts in long bones. However, Fas and FasL functions in osteogenesis remain controversial. As most of studies dealing with Fas/FasL system in bone formation were performed in endochondral mode...