Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp123 | Cell biology: osteoblasts and bone formation | ECTS2014

miR-468 controls Runx2 expression during early differentiation of Runx2 in mice

Cabon Owen , Geoffroy Valerie

We investigated the ability of microRNAs to regulate osteoblast differentiation by controlling distinct aspects of the differentiation process. We have identified by microRNAs microarray a set of miRNAs that are differentially regulated during differentiation of the two osteoblast cell lines MC3T3-E1 and C3H10T1/2. We focused on miR-468 that is a potential regulator of Runx2.In our microarray analysis miR-468 was expressed at a high level and was strongl...