Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p242 | Genetics and Epigenetics | ECTS2016

A family with Paget disease of bone caused by a novel mutation of hnRNPA2B1 gene

Qi Xuan , Pang Qianqian , Wang Jiawei , Zhao Zhen , Wang Ou , Xu Lijun , Mao Jiangfeng , Jiang Yan , Li Mei , Xing Xiaoping , Yu Wei , San A , Xia Weibo

Paget disease of bone (PDB) is a common metabolic bone disease characterized by increased bone resorption and disorganized bone formation which can affect single or multiple sites of bone. Although the exact cause of PDB is still controversial, genetic factor is considered to play an important role in PDB. The causative gene of classical PDB was identified as Q8STM1 gene. Familial expansile osteolysis caused by the mutation of TNFRSF11A(RANKL) gene a...

ba0005p430 | Other diseases of bone and mineral metabolism | ECTS2016

Type 2 diabetes mellitus increase the risks of incident osteoporotic fractures in Chinese postmenopausal women: a 5-year prospective study

Jiajue Ruizhi , Qi Xuan , Jiang Yan , Wang Qiuping , Wang Wenbo , Pei Yu , Wang Xiran , Huang Wei , Zheng Xin , Ning Zhiwei , Wang Ou , Li Mei , Xing Xiaoping , Yu Wei , Xu Ling , Xia Weibo

Purpose: The aim of this 5-year prospective study was to investigate the association between type 2 diabetes mellitus (T2DM) and incident osteoporotic fracture (IOF) in Chinese postmenopausal women aged 50 years or older.Methods: We included 826 subjects, participating in both the baseline (2007–2008) and follow-up (2012–2013) studies. Based on the diagnosis of T2DM, subjects were first individualized into Non-T2DM and T2DM groups, which were t...