Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp295 | Osteoporosis: treatment | ECTS2014

Bisphosphonate treatment of postmenopausal osteoporosis and circulating levels of DKK1 and sclerostin: effects of treatment regimens

Idolazzi Luca , Gatti Davide , Viapiana Ombretta , Fracassi Elena , Dartizio Carmela , Risoli Marta , Rossini Maurizio , Adami Silvano

The coupling of bone formation to bone resorption during treatment of postmenopausal osteoporosis with antiresorbers might be related to changes in Wnt/β-catenin signalling. We compared the effects of two bisphosphonate treatments on two Wnt inhibitors sclerostin (SOST) and Dickkopf-related protein 1 (DKK1). The study population included 72 women with postmenopausal osteoporosis participating simultaneously in two multicenter, placebo controlled trials. The patients were ...

ba0005p354 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Bone metabolism in patients with anorexia nervosa and amenorrhea

Gatti Davide , Idolazzi Luca , el Ghoch Marwan , Viapiana Ombretta , Calugi Simona , Rossini Maurizio , Caimmi Cristian , Braga Vania , Radetti Giorgio , Adami Silvano , Grave Riccardo Dalle

Context: Anorexia nervosa (AN) occurs predominantly in females, most frequently during adolescence and it is generally associated with amenorrhoea. AN increases the risk for impaired bone health and for low bone mineral density (BMD) by a mechanism which has not been yet well defined.Objective: The study purpose was to further characterize bone metabolism in AN with amenorrhoea, and so with oestrogen deficiencyDesign: AN patients w...

ba0001oc1.1 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Disease-specific perception of fracture risk and incident fracture rates among postmenopausal women: findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Gregson Celia , Dennison Elaine , Compston Juliet , Adami Silvano , Adachi Jonathan , Anderson Frederick , Boonen Steven , Chapurlat Roland , Diez-Perez Adolfo , Greenspan Susan , Hooven Frederick , Lacroix Andrea , Nieves Jeri , Netelenbos J Coen , Pfeilschifter Johannes , Rossini Maurizio , Roux Christian , Saag Kenneth , Silverman Stuart , Siris Ethel , Watts Nelson , Wyman Allison , Cooper Cyrus

Patients with improved health understanding have greater autonomy over, and motivation towards, health-related lifestyles. We compared self-perceived fracture risk and 3-year incident fracture rates in postmenopausal women for a range of co-morbid diseases using data from the Global Longitudinal study of Osteoporosis in Women (GLOW).GLOW is an international cohort study involving 723 physician practices across 10 countries in Europe, North America, Austr...