Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp314 | Osteoporosis: evaluation and imaging | ECTS2013

Communication of fracture risk and treatment benefit in terms of ‘bone health age’ using FRAX or Qfracture

Abrahamsen Bo , Rubin Katrine Hass , Hansen Carrinna , Brixen Kim

Introduction: Communication of absolute and relative risks is challenging despite the development of tools to quickly derive absolute fracture risk estimates from risk factors with or without BMD. We speculated that back-transformation of risks to a risk age could make for a clearer message and at the same time increase agreement between risk algorithms.Results: The algorithms differed less in estimated bone health age than in percent risk. A 60 years ol...

ba0003oc4.6 | Genetics of bone disease | ECTS2014

Gout is associated with an excess risk of osteoporotic fracture: findings from a Danish registry

Dennison Elaine , Rubin Katrine H , Harvey Nick , Walker-Bone Karen E , Schwarz Peter , Cooper Cyrus , Abrahamsen Bo

Objective: Although metabolic syndrome is common in gout patients, recent reports that bone mineral density may actually be reduced (and falls common) in this group have led researchers to hypothesise that osteoporotic fracture may be more common in subjects with gout than in healthy controls. We tested this hypothesis in a national Danish registry.Material and Methods: We identified subjects as new users of allopurinol, a proxy for gout, for the years 1...

ba0003pp360 | Osteoporosis: treatment | ECTS2014

Predictors of second fracture while on treatment with oral bisphosphonates: a multinational retrospective cohort study

Hawley Sam , Wallace Gemma , Javaid M Kassim , Rubin Katrine , Judge Andrew , Vestergaard Peter , Eastell Richard , Diez-Perez Adolfo , Arden Nigel K , Cooper Cyrus , Prieto-Alhambra Daniel , Abrahamsen Bo

Objective: To identify predictors of inadequate response to oral bisphosphonate therapy, defined as the incidence of ≧2 fractures while on treatment among incident oral bisphosphonate users with high refill compliance (≧80%).Material and methods: Data from computerized records and pharmacy invoices were obtained from SIDIAP (Catalonia, E) and Danish Health Registries (DK) for all incident users of oral bisphosphonates in 2006–2007 and 2000&#15...