Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p113 | Cancer and bone: basic, translational and clinical | ECTS2016

Dendritic glycopolymers as efficient drug delivery systems for retarded release of bortezomib from calcium phosphate cements

Mamitzsch Bettina , Striegler Christin , Schumacher Matthias , Gelinsky Michael , Muller Martin , Seckinger Anja , Voit Brigitte , Appelhans Dietmar

Calcium phosphate cements (CPC) are used as bone graft substitute, e.g. in the treatment of lytic bone lesions in multiple myeloma. CPC provide crucial advantages, such as osteoconductivity, biodegradability and the potential drug loading. Though, it lacks retarded drug release for short-/long-term treatment due to the free diffusion of small molecules through the micropores in the CPC.Thus we present dendritic glycopolymers (DG) consisting of poly(ethyl...