ba0003pp130 | Cell biology: osteoblasts and bone formation | ECTS2014
, LeBlanc Solange
, Jakob Franz
, Schutze Norbert
, Schilling Tatjana
Osteoporosis is generally accompanied by the fatty degeneration of the bone marrow. The enhanced deposition of adipocytes may result from adipogenic differentiation of bone-marrow mesenchymal stem cells (MSC) and from the adipogenic conversion of osteoblastic cells respectively. Thus, whether this clinical observation is a cause of the disease or rather a reaction of the afflicted bone marrow remains to be elucidated.Previous microarray and bioinformatic...