Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp220 | Cell biology: osteoclasts and bone resorption | ECTS2013

Modulation of osteoclastogenesis by fluoroquinolones on nano- and micro-structurated hydroxyapatite surfaces

Ribeiro Sofia , Costa-Rodrigues Joao , Fernandes Maria

Hydroxyapatite (HA) has been widely used as a biocompatible ceramic in many areas of medicine, mainly for contact with bone tissue, due to its resemblance to mineral bone. Owing to the nanofeatures of bone tissue, new nano-HA based materials are among the most promising challenges in bioactive ceramics. Recently, it was observed that fluoroquinolones have the ability to interfere with osteoclastogenesis, in standard polystyrene cell culture plates. The aim of this work is to a...