Searchable abstracts of presentations at key conferences on calcified tissues

ba0002p82 | (1) | ICCBH2013

The influence of sclerostin serum levels on bone mineral density and body composition in patients with Rett syndrome and healthy adolescent girls

Caffarelli Carla , Tanzilli Loredana , Pitinca Maria Dea Tomai , Hayek Joseph , Francolini Valentina , Franci Beatrice , Nuti Ranuccio , Gonnelli Stefano

Objective: Sclerostin, product of the SOST gene, is an important determinant of bone formation and resorption. Rett patients, frequently present marked decreases in bone mineral density (BMD) beyond that expected from disuse atrophy. However, sclerostin has not been yet examined in Rett subjects as a potential mediator of impaired bone metabolism.Methods: This study aimed to investigate whether there is any associations between sclerostin levels, body co...