Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp40 | Bone biomechanics and quality | ECTS2013

Prediction of vertebral body stiffness in patients with multiple myeloma using qCT-based finite element models

Campbell Graeme , Graeff Christian , Giravent Sarah , Thomsen Felix , Pena Jaime , Wulff A , Gunther A , Gluer Claus C , Borggrefe Jan

Multiple myeloma (MM) is associated with lytic bone destruction leading to high fracture incidence in the vertebrae. Accurate assessment of fracture risk is required for physicians to determine the necessity for surgery. This risk is currently determined by examining lesion size or number; however, this method does not consider the biomechanical attributes of the bone. Finite element (FE) modelling can simulate mechanical loading on vertebral bodies, and estimate mechanical in...

ba0003pp214 | Osteoporosis: evaluation and imaging | ECTS2014

Bone marrow densitometry by clinical high resolution computed tomography of human vertebrae

Pena Jaime , Campbell Graeme , Damm Timo , Barkmann Reinhard , Waldhausen Sonja , Thomsen Felix , Krause Matthias , Puschel Klaus , Gluer Claus C

Bone mineral density (BMD) as measured by quantitative computed tomography (QCT) is biased by the variable marrow composition since marrow fat reduces the apparent BMD. We developed a marrow densitometry (MD) method that identifies subvolumes in the vertebrae that consist of bone marrow only (bone voids) and determines their average mineral equivalent density values. The method was developed for use with in vivo high resolution QCT (HR-QCT). HR-QCT still has limited s...