Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p395 | Osteoporosis: treatment | ECTS2016

Acute kidney injury after a single intravenous zoledronic acid administration in patients with osteoporosis

Cipriani Cristiana , Clementelli Carolina , Fassino Valeria , Manai Rizieri , Danese Vittoria , Cecchetti Veronica , Ferrone Federica , Pepe Jessica , Minisola Salvatore

Safety data on zoledronic acid (ZA) administration for osteoporosis suggest potential kidney toxicity; indeed, it is not indicated in patients with impaired renal function. PatientsÂ’ clinical monitoring usually includes glomerular filtration rate (GFR) evaluation; no study addressed the issue of the early kidney injury. We evaluated the early (within 3 months) effect of iv ZA on renal function defining the potential role of AKI biomarkers in unveiling subtle damage.<p...