Searchable abstracts of presentations at key conferences on calcified tissues

ba0001oc2.3 | Bone quality and fracture repair - animal models | ECTS2013

Low-magnitude high-frequency vibration improves fracture healing in aged, ovariectomized mice

Wehrle Esther , Bindl Ronny , Wehner Tim , Heilmann Aline , Fischer Lena , Noland Jarrod , Amling Michael , Ignatius Anita

Introduction: Fracture healing is impaired in aged and osteoporotic patients. Because bone formation is tightly regulated by the mechanical conditions in the fracture gap and because suitable mechanical stimuli improve fracture healing (Claes et al. 1998), we investigated whether low-magnitude high-frequency vibration (LMHFV; Rubin et al. 2004) is able to improve delayed fracture healing induced by age and ovariectomy in mice.Sudy desig...