Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p142 | Cell biology: osteoblasts and bone formation | ECTS2016

Regulation of genes involved in the integrin signalling pathway induced by titanium with nanotopography

Lopes Helena , Freitas Gileade , Florio Pedro , de Oliveira Paulo , Rosa Adalberto , Beloti Marcio

Titanium (Ti) surface with nanotopography induces osteoblast differentiation, at least in part, by upregulating the expression of α1/β1 integrins. Thus, we hypothesized that other potential candidates from the integrin signalling pathway may be involved in the osteogenic potential of nanotopography. In this context, the aim of this study was to compare the expression of integrin family members of cells grown on nanotopography with machined surface. Machined Ti discs ...