Bone Abstracts (2016) 5 P335 | DOI: 10.1530/boneabs.5.P335

Qulaity of life of patients with osteoporotic vertebral compression fractures

Si Young Park1, Ho Jin Jung1, Ye Soo Park2, Hyoung Yeon Seo3, Jae Chul Lee4, Byung Joon Shin4 & Ki Chan An5


1Korea University, Seoul, Republic of Korea; 2Hanyang University, Seoul, Republic of Korea; 3Chonnam National University, Gwangju, Republic of Korea; 4Soonchunhyang University, Seoul, Republic of Korea; 5Inje University, Busan, Republic of Korea.


Introduction: As Korean society have been entered to aging population, osteoporosis is considered one of the most important disease in the elderly. Osteoporotic vertebral compression fractures can affect to patient’s quality of life. But, in Korea, there is few studies about this, so we investigated.

Aim: To evaluate the quality of life of patients with vertebral compression fracture.

Methods: This study was performed in multicenter, prospectively, using interview. Study population was over 50 years old patients who had osteoporotic vertebral compression fracture recently and treated for the fracture. We investigated demographic features and information about vertebral fracture, such as timing of diagnosis, level of fracture, treatment methods. And satisfaction level, VAS pain scale, EQ-5D scale, Oswestry Disability Index were also recorded from population. Statistical analysis was used, and a factors were analyzed which related to quality of life.

Results: Total 304 patients were included, average period from fracture to participation of interview was 9.4 months. Multilevel fracture patients were 106. About 30% of patients were not received bone mineral density examination, and osteoporotic treatment. Mean t-score of bone mineral density was −2.75±0.7. About 40% of patients did not have trauma history or clear memory of trauma. EQ-5D index was significantly influenced by gender and age, and significantly correlated with ODI score (correlation coefficient 0.825). Multivarient analysis revealed that multilevel involvement, bone mineral density were correlated significantly with EQ-5D index.

Conclusion: Patients with OVCFs had very low quality of life despite of fracture healing. EQ-5D is adequate tool of evaluate quality of life of osteoporotic vertebral compression fracture patients in Korea. EQ-5D index has significant relationship with ODI score. And, multilevel involvement and bone mineral density can be a factor which affects to quality of life.

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