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Bone Abstracts (2014) 3 PP246 | DOI: 10.1530/boneabs.3.PP246

Osteoporosis: evaluation and imaging

Do osteophytes protect femoral neck against fracture in osteoarthritis?

Sofoclis Bakides, George Sakellariadis, Angelos Charamis, Kiriakos Drivas, Charilila-Loukia Ververeli, Semiramis Zakaki, Vasileios Kapagiannis & George Papageorgiou

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Molaoi General Hospital, Lakonia, Greece.


Introduction: The FRAX tool can be used to assess absolute fracture risk, but the majority of treatment decisions are still based on measurements by DEXA. In remote rural Greek areas, after the socioeconomy crisis, access to the nearest DEXA facility became more difficult.

Purpose: Role of combined QUS and FRAX in the identification of low risk patients who do not require DEXA applying a FRAX threshold of 4% for the 10-year major osteoporotic fracture probability (10YMOFP) like in UK studies, where the incidence and prevalence of osteoporosis is higher than Greece.

Methods: Population study 214 women aged 40–60 years. Clinical risk factors evaluated with FRAX (FRF), BMD measured using heel QUS.

Results: Mean age was 51, 52 years and mean BMI: 27.28 kg/m2. We found that 52 and 33 out of 90 and 124 women (57.77 and 26.61%) who had (10YP) <4% had also T<−1. In total 12 out of 214 were found eligible for treatment after DEXA measurement (four and eight for the age groups: 40–49, 50–60, respectively). Our results:

(10YMOFP) <4%, NO (FRF)(10YMOFP) <4%, 1–2 (FRF)(10YMOFP) >4%, 1–2 (FRF)
AgeT<−1−1<T<−2,5T<−1−1<T< −2,5T<−1−1<T<−2,5
40–49 (n=90)20103210411
50–60 (n=124)22261131440
Total (n=214)423643131851

Conclusions: We went onto determine if FRAX and QUS could be employed to ‘pre-screen’ patients at low osteoporosis risk. In our referral population 42 out of 214 women (19.6%) who had (10YMOFP) <4% and no (FRF), all had T<−1 (QUS and DEXA).

We conclude that furher studies are needed for the identification threshold of low risk patients. This would have resulted in fewer scans representing a reduction in workload and cost.

Volume 3

European Calcified Tissue Society Congress 2014

Prague, Czech Republic
17 May 2014 - 20 May 2014

European Calcified Tissue Society 

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