Introduction: The FRAX tool can be used to assess absolute fracture risk, but the majority of treatment decisions are still based on measurements by DEXA. In remote rural Greek areas, after the socioeconomy crisis, access to the nearest DEXA facility became more difficult.
Purpose: Role of combined QUS and FRAX in the identification of low risk patients who do not require DEXA applying a FRAX threshold of 4% for the 10-year major osteoporotic fracture probability (10YMOFP) like in UK studies, where the incidence and prevalence of osteoporosis is higher than Greece.
Methods: Population study 214 women aged 4060 years. Clinical risk factors evaluated with FRAX (FRF), BMD measured using heel QUS.
Results: Mean age was 51, 52 years and mean BMI: 27.28 kg/m2. We found that 52 and 33 out of 90 and 124 women (57.77 and 26.61%) who had (10YP) <4% had also T<−1. In total 12 out of 214 were found eligible for treatment after DEXA measurement (four and eight for the age groups: 4049, 5060, respectively). Our results:
|(10YMOFP) <4%, NO (FRF)||(10YMOFP) <4%, 12 (FRF)||(10YMOFP) >4%, 12 (FRF)|
Conclusions: We went onto determine if FRAX and QUS could be employed to pre-screen patients at low osteoporosis risk. In our referral population 42 out of 214 women (19.6%) who had (10YMOFP) <4% and no (FRF), all had T<−1 (QUS and DEXA).
We conclude that furher studies are needed for the identification threshold of low risk patients. This would have resulted in fewer scans representing a reduction in workload and cost.
17 May 2014 - 20 May 2014