ECTS2014 Poster Presentations Osteoporosis: pathophysiology and epidemiology (38 abstracts)
Background: It is now known that the osteoporosis starts developing childhood. Childrens age is characterized by intensive accumulation of bone mass. By the end of puberty the level of bone mass in many parts of the skeleton reaches 86% of the bone mass of an adult and in some parts it reaches 100%.
The processes of bone metabolism closely connected with the level of the vitamin D, in the body because it has a pronounced effect on calcium homeostasis.
Aim: To explore calcium and vitamin D daily intake level, determine the frequency of vitamin D sufficiency to bone mineral density (BMD) in Ukrainian schoolchildren.
Methods: It was examined 304 Ukrainian schoolchildren aged 1017 years. Of these 118 residents were of the west side, 91 and 95 north-eastern region of the country. Methods conducted chemiluminescent content of 25 OH vitamin D, parathyroid hormone (PTH), diet study using questionnaires, ultrasound densitometry.
Results: Only 2.7% observed had normal calcium intake level, most children (56.8%) took 500 mg of calcium per day. 60.1% children had deficiency of vitamin D in diet. Deficiency of vitamin D serum levels 25 (OH) D was 88.5%, lack of 8.8% and only 2.6% had normal levels. Fractures were recorded in 16% of patients, 54.5% of them low energy. It was determined negative significant correlation between PTH and 25-OH vitamin D. Low mineral density was registered in 8.7% children. No significant correlation between 25-OH vitamin D and BMD.
Conclusions: High level of vitamin D deficiency, poor calcium and vitamin D level intake, frequent osteopenic syndrome in children make doctors to research the effective methods of treatment and prophylactics of revealed disorders.
17 May 2014 - 20 May 2014