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Abstract unavailable

ba0004p1

The assessment of bone regulatory pathways in children with malignant bone tumors

Ambroszkiewicz Jadwiga Gajewska Joanna Chelchowska Magdalena Rogowska Elzbieta Rychlowska-Pruszynska Magdalena

¹Screening Department Institute of Mother and Child, Warsaw, Poland, ²Department of Oncological Surgery for Children and Youth Institute of Mother and Child, Warsaw, Poland.

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PHEX, DMP1 and FGF23 mutations in a Malaysian hypophosphatemic rickets patient

Razali Nurul Nadirah Ting Tzer Hwu Thilakavathy Karuppiah

¹Department of Obstetrics and Gynaecology, Department of Paediatrics, Clinical Genetics Unit, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia; ²Department of Paediatrics, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia; ³Genetics and Regenerative Research Centre, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia.

ba0004p3

Bone turnover markers and bone mineral density after 12-month weight loss therapy in obese children

Gajewska Joanna Klemarczyk Witold Ambroszkiewicz Jadwiga Chelchowska Magdalena Weker Halina

Institute of Mother and Child, Warsaw, Poland.

ba0004p4

Vitamin D and decreased bone density in children

Bazarra-Fernandez Antonio

La Corunna University Hospital Trust, Culleredo, La Coruña, Spain.

ba0004p5

Bisphosphonate treatment of melorheostosis: A case report

Akinci Aysehan Dundar Ismail Dundar Sigirci Ahmet

Inonu University, Malatya, Turkey.

ba0004p6

History of meconium ileus affects bone health and body composition in young patients with cystic fibrosis

Doulgeraki Artemis Petrocheilou Argyri Chrousos George Petrocheilou Glykeria Monopolis Ioannis Doudounakis Stavros-Eleftherios Kaditis Athanasios

¹Institute of Child Health, Agia Sophia Children’s Hospital, Athens, Greece; ²Cystic Fibrosis Center, Agia Sophia Children’s Hospital, Athens, Greece; ³First Department of Pediatrics, Paediatric Pulmonology Unit, University of Athens School of Medicine, Agia Sophia Children’s Hospital, Athens, Greece.

ba0004p7

Body composition profile of patients with Duchenne muscular dystrophy living in a country with the obesity epidemic

Doulgeraki Artemis Katsalouli Marina Petrocheilou Glykeria Paspati Ioanna Athanasopoulou Helen Monopolis Ioannis

¹Institute of Child Health, Agia Sophia Children’s Hospital, Athens, Greece; ²Neuromuscular Unit, Agia Sophia Children’s Hospital, Athens, Greece; ³Department of Paediatric Orhopaedics, Penteli Children’s Hospital, Athens, Greece.

ba0004p8

Vitamin D supplementation can improve velocity of growth in children with vitamin D deficiency which are in treatment with RHGH for growth hormone deficiency

Galesanu Corina Grozavu Ilinka Alexandru Florescu A

Endocrinology, University of Medicine and Pharmacy ‘Gr.T.Popa’, Iasi, Romania.

ba0004p9

Infantile Blount's disease: histopathologic changes in the proximal tibial metaphysis -- comparison between medial and lateral specimens

Hollman Freek Vroemen Pascal Rompa Paul Moh Prosper van Rhijn Lodewijk Weltink Tim Staal Heleen

Maastricht University Medical Centre, Maastricht, The Netherlands.

ba0004p10

Effects of bisphosphonate for the development of scoliosis in children with osteogenesis imperfecta

Kashii Masafumi Kanayama Sadaaki Kitaoka Taichi Makino Takahiro Kaito Takashi Kubota Takuo Namba Noriyuki Yamamoto Takehisa Ozono Keiichi Yoshikawa Hideki

¹Osaka University Graduate School of Medicine, Suita, Osaka, Japan; ²Minoh Municipital Hospital, Minoh, Osaka, Japan.

ba0004p11

Elevated plasma c-terminal fibroblast growth factor, but not intact FGF23 or soluble Klotho, is associated with left ventricular hypertrophy in pediatric chronic hemodialysis patients

Shah Shweta Brewer Eileen Srivaths Poyyapakkam

Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA.

ba0004p12

Galactosyltransferase-1 deficiency: a novel cause of bone fragility due to impaired proteoglycan synthesis

Moon Rebecca Salter Claire Foulds Nicola Davies Justin

¹Paediatric Endocrinology, University Hospitals Southampton NHS Foundation Trust, Southampton, UK; ²MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; ³Wessex Clinical Genetics Service, University Hospitals Southampton NHS Foundation Trust, Southampton, UK.

ba0004p13

Accuracy of parental recall of children's lifetime fracture prevalence: implications for investigation of childhood osteoporosis

Moon Rebecca Lim Adelynn Farmer Megan Segaran Avinash Clarke Nicolas Davies Justin

¹Paediatric Endocrinology, University Hospitals Southampton NHS Foundation Trust, Southampton, UK; ²MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; ³Paediatric Orthopaedics, University Hospitals Southampton NHS Foundation Trust, Southampton, UK.

ba0004p14

Fibrous dysplasia in McCune Albright syndrome; treatment and follow up

Gokeen Damla Ozen Samim Ozcan Nurhan Darcan Sukran

Department of Ped Endocrinology, Ege Universtity Fac of Medicine, Izmir, Turkey.

ba0004p15

Genotype in patients with osteogenesis imperfecta using a targeted exome sequencing: correlation with phenotype

Kubota Takuo Ohata Yasuhisa Bizaoui-Auffret Varoona Nawa Nobutoshi Nakayama Hirofumi Yamamoto Keiko Fujiwara Makoto Kitaoka Taichi Takakuwa Satoshi Namba Noriyuki Ozono Keiichi

ba0004p16

MRI features as surrogate markers of X-linked hypophosphatemic rickets activity

Lempicki Marta Rothenbuhler Anya Merzoug Valerie Franchi-Abella Stephanie Chaussain Catherine Linglart Agnes Adamsbaum Catherine

¹APHP, Department of Pediatric Radiology, Hôpital de Bicêtre and Paris Sud University, Le Kremlin-Bicêtre, France; ²APHP, Department of Pediatric Endocrinology, Reference Center for Rare Disorders of Calcium and Phosphorus Metabolism, Bicêtre Hospital and Paris Sud University, Le Kremlin-Bicêtre, France; ³APHP, Department of Odontology, Bretonneau Hospital and 6EA2496 University Paris Descartes, Paris, France.

ba0004p17

A novel mutation in CYP24A1 gene in an infant with severe hypercalcemia and unique neurological presentation

Levy-Shraga Yael Pinhas-Hamiel Orit Dinour Dganit Modan-Moses Dalit

¹Pediatric Endocrine and Diabetes Unit, Sheba Medical Center, Edmond and Lily Safra Children’s Hospital, Tel-Hashomer, Ramat Gan, Israel; ²Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel; ³Department of Nephrology and Hypertension, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.

ba0004p18

The role of body composition in the relationship between lifestyle factors and bone parameters of young children

Sioen Isabelle Solis-Trapala Ivonne De Schepper Jean Roggen Inge Goemaere Stefan De Henauw Stefaan Ward Kate

¹Ghent University, Ghent, Belgium; ²MRC Human Nutrition Research, Cambridge, UK; ³Vrije Universiteit Brussel, Brussels, Belgium; ⁴Ghent University Hospital, Ghent, Belgium.

ba0004p19

Bone mineral density in patients with autosomal recessive osteopetrosis after hematopoietic cell transplantation

Petryk Anna Polgreen Lynda E Dengel Donald R Defor Todd E Orchard Paul

¹University of Minnesota, Minneapolis, Minnesota, USA; ²Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.

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Efficacy of GH therapy in short patients affected hypochondroplasia

Nakano Yukako Harada Daisuke Kashiwagi Hiroko Seino Yoshiki

JCHO Osaka Hospital, Osaka City, Osaka, Japan.

ba0004p21

Racing to better bone health! A 6-month calcium and vitamin D randomised controlled trial in young male jockeys

Silk Leslie Greene David Baker Michael

Australian Catholic University, Strathfield, New South Wales, Australia.

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Relationship of IGF1 and bone parameters in 7--16 year old apparently healthy Indian children

Kajale Neha Ekbote Veena Palande Sonal Shilvant Dhanashri Mandlik Rubina Khadilkar Vaman Mughal Zulf Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India; ²Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p23

Bone status of Indian children and adolescents with type 1 diabetes mellitus

Mandlik Rubina Parthasarathy Lavanya Khadilkar Vaman Chiplonkar Shashi Phanse-Gupte Supriya Kajale Neha Mughal Zulf Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India; ²Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p24

Sitting time has a stronger effect on bone than moderate plus vigorous activity

Binkley Teresa Weidauer Lee Specker Bonny

South Dakota State University, Brookings, South Dakota, USA.

ba0004p25

Effects of running bike use on bone quality in non-ambulant children with cerebral palsy: a pilot study

Bryant Elizabeth Cowan Donna Walker-Bone Karen

¹Chailey Heritage Clinical Services, Sussex Community NHS Trust, Lewes, East Sussex, UK, ²Centre for Health Research, University of Brighton, Eastbourne, East Sussex, UK, ³MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, Hampshire, UK.

ba0004p26

Bone mineral density and clinical outcome after intravenous bisphosphonate discontinuation in children with osteogenesis imperfecta

Bowden Sasigarn Heksch Ryan Hickey Scott Mahan John

Nationwide Children’s Hospital/The Ohio State University, Columbus, OH, USA.

ba0004p27

Year-round cord blood vitamin D concentrations in women from diverse ethnical backgrounds in a Mediterranean area in Spain

Guagnelli Miguel Angel Yeste Diego Ferrer Roser Comas Inmaculada Carrascosa Antonio

¹Hospital Maternoinfantil Vall d’Hebron, Barcelona, Catalunya, Spain; ²Hospital del Vendrell, El Vendrell, Catalunya, Spain.

ba0004p28

Type 1 diabetes mellitus may predispose to lower bone mineral density through lower osteoblast signaling from increased levels of Dickkopf-1

Doulgeraki Artemis Tsentidis Charalampos Gourgiotis Dimitrios Kossiva Lydia Marmarinos Antonios Karavanaki Kyriaki

¹Department of Bone and Mineral Metabolism, Institute of Child Health, Agia Sophia Children’s Hospital, Athens, Greece; ²Second Pediatric Department, Diabetic Clinic, University of Athens, ‘P&A Kyriakou’ Children’s Hospital, Athens, Greece; ³Second Pediatric Department, Biochemistry Laboratory, University of Athens, ‘P&A Kyriakou’ Children’s Hospital, Athens, Greece.

ba0004p29

Whole-body MR imaging as diagnostic tool in children with hereditary multiple osteochondromas

Staal Heleen Dremmen Marjolein Robben Simon Witlox Adhiambo van Rhijn Lodewijk

¹Department of Orthopaedic Surgery, Research school CAPHRI, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands; ²Department of Radiology, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.

ba0004p30

Mineral metabolism in children with autosomal dominant polycystic kidney disease

De Rechter Stephanie Bacchetta Justine Dubourg Laurence Cochat Pierre Van Dyck Mieke Evenepoel Pieter Levtchenko Elena Mekahli Djalila

¹Department of Pediatric Nephrology, Leuven, Belgium; ²Laboratory of Pediatrics, KU Leuven, Leuven, Belgium; ³Centre de Référence des Maladies Rénales Rares, Hospices Civils de Lyon, Bron, France; ⁴Department of Internal Medicine, Division of Nephrology, Leuven, Belgium.

ba0004p31

Characteristics of Malawian children undergoing corrective bone surgeries of rickets-like lower limb deformities

Braithwaite Vickie S Greenwood Carla L Bishop Nicholas J Cashman John Prentice Ann

¹MRC Human Nutrition Research, Cambridge, UK; ²University of Sheffield, Sheffield, UK; ³Beit Cure Orthapaedic Hospital, Blatyre, Malawi; ⁴MRC Keneba, West Kiang, Gambia.

ba0004p32

In utero effects of iron status on infant fibroblast growth factor-23 and mineral metabolism

Braithwaite Vickie S Prentice Ann Darboe Momodou K Prentice Andrew M Moore Sophie E

¹MRC Human Nutrition Research, Cambridge, UK; ²MRC Keneba, West Kiang, Gambia; ³MRC International Nutrition Group, London and The Gambia, UK.

ba0004p33

Abstract unavailable

ba0004p34

Spinal muscular atrophy: another non-ambulatory population at risk for low bone mineral density

Kecskemethy Heidi Bachrach Steven Harcke H Theodore

¹Nemours/A.I. duPont Hospital for Children, Wilmington, DE, USA; ²Thomas Jefferson University, Philadelphia, PA, USA.

ba0004p35

Bone mineral density, pubertal status and ability to walk are associated to fracture incidence in patients with Rett syndrome

Rothenbuhler Anya Esterle Laure Lahlou Najiba Bienvenu Thierry Bahi-Buisson Nadia Linglart Agnes

¹Pediatric Endocrinology, Bicêtre University Hospital, Paris, France; ²Laboratoire d’Hormonologie spécialisée et métabolisme, Hôpital Cochin, Paris, France; ³Institut Cochin, Paris, France; ⁴Pediatric Neurology, Necker University Hospital, Paris, France.

ba0004p36

Teriparatide following bisphosphonates in the treatment of osteoporosis in post-pubertal teenagers

Alon Uri Monachino Penny

Bone and Mineral Disorders Clinic, Children’s Mercy Hospital, University of Missouri at Kansas City, Kansas City, MO, USA.

ba0004p37

Serum 25-vitamin D level is lower in African American compared to Caucasian children

Srivastava Tarak Sebestyen Judith Alon Uri

Bone and Mineral Disorders Clinic, Children’s Mercy Hospital, University of Missouri at Kansas City, Kansas City, MO, USA.

ba0004p38

Fracture and bone mineral density outcomes after bisphosphonate discontinuation in children with osteogenesis imperfecta treated with zoledronic acid compared to pamidronate

Heksch Ryan Bowden Sasigarn Hickey Scott Mahan John

Nationwide Children’s Hospital/The Ohio State University, Columbus, OH, USA.

ba0004p39

Painful hip in 19-months old represents an intertrochanteric fracture following a low energy injury

Peev Peter Obretenov Vasil

¹Ealing Hospital, LNWH NHS Trust, London, UK; ²Naval Hospital, Varna, Varna, Bulgaria.

ba0004p40

Percutaneously performed image-guided radiofrequency ablation for the treatment of a unifocal eosinophilic granuloma of the femur in a 16-year-old boy

Papavasiliou Kyriakos Bintoudi Antonia Karanassos Marinos Vlaxodimos Apostolos Pellios Stavros Tsitouridis Ioannis Kirkos John

¹Third Orthopaedic Department Aristotle University of Thessaloniki Medical School, Papageorgiou General Hospital, Thessaloniki, Greece; ²Department of Radiology, Papageorgiou General Hospital, Thessaloniki, Greece.

ba0004p41

Levels of vitamin D according to severity of motor function disorder and the level of bone mineral density in children with cerebral palsy

Zvekic-Svorcan Jelena Nenadov Natasa Krasnik Rastislava Mikov Aleksandra Vulovic Mirela Demesi-Drljan Cila Bekic Vera

¹Special Hospital for Rheumatic Diseases, Novi Sad, Serbia; ²Home ‘Veternik’, Veternik, Serbia; ³Clinic of Child Habilitation and Rehabilitation, Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Serbia; ⁴Medical Faculty, University of Novi Sad, Novi Sad, Serbia.

ba0004p42

Efect of nutritional status on bone density in children with cerebral palsy

Krasnik Rastislava Zvekic-Svorcan Jelena Nenadov Natasa Mikov Aleksandra Demesi-Drljan Cila Vulovic Mirela Bekic Vera

¹Clinic of Child Habilitation and Rehabilitation, Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Serbia; ²Special Hospital for Rheumatic Disease, Novi Sad, Serbia; ³Home Veternik, Veternik, Serbia; ⁴Medical Faculty, University of Novi Sad, Novi Sad, Serbia.

ba0004p43

Closed image-guided vs open biopsies in children with bone lesions: a retrospective review of 112 biopsies performed on 104 patients

Papavasiliou Kyriakos Bintoudi Antonia Fontalis Andreas Karanassos Marinos Pellios Stavros Tsitouridis Ioannis Kirkos John

¹Third Orthopaedic Department, Aristotle University of Thessaloniki Medical School, Papageorgiou General Hospital, Thessaloniki, Greece; ²Department of Radiology Papageorgiou General Hospital, Thessaloniki, Greece.

ba0004p44

Skeletal dysplasia with short stature and a Larsen-like phenotype due to a homozygous mutation in B3GAT3

Steichen-Gersdorf Elisabeth Laccone Franco

¹Medical University, Innsbruck, Austria; ²Institute of Medical Genetics, Vienna, Austria.

ba0004p45

Evaluation of the use of a dynamic elastomeric fabric orthosis to improve truncal stability in a young child with osteogenesis imperfecta

Edwards Karen Hupin Emilie Cheung Moira DeVile Catherine

Great Ormond Street Hospital for Children, London, UK.

ba0004p46

Ethnic and gender differences in metacarpal dimensions in black and white South African children from pre-puberty through adolescence

Magan Ansuyah Micklesfield Lisa Norris Shane Pettifor John

Faculty of Health Sciences, MRC/Wits Developmental Pathways for Health Research Unit, University of the Witwatersrand, Johannesburg, South Africa.

ba0004p47

Bone mineral density, vertebral compression fractures and pubertal delay in patients with autosomal recessive epidermolysis bullosa

Cheung Moira Bozorgi Niloofar Mellerio Jemima Fewtrell Mary Allgrove Jeremy Brain Caroline Martinez Anna

Great Ormond Street Hospital NHS Foundation Trust, London, UK.

ba0004p48

Using high-resolution peripheral quantitative computed tomography (HRpQCT) to better understand the skeletal response to exercise

Edwards Lauren Skerry Tim Paggiosi Margaret Offiah Amaka

University of Sheffield, Sheffield, UK.

ba0004p49

‘Double trouble': Duchenne muscular dystrophy and osteogenesis imperfecta in one patient - a case report

Bayer Milan Taslerova Renata Mrazova Lenka Fajkusova Lenka Oslejskova Hana

¹Department of Pediatrics, Charles University Prague, University Hospital in Hradec Králové, Hradec Králové, Czech Republic; ²Centre of Molekular Biology and Gene Therapy, University Hospital Brno, Brno, Czech Republic; ³Department of Pediatric Neurology, Masaryk University, University Hospital Brno, Brno, Czech Republic.

ba0004p50

Abstract unavailable

ba0004p51

Association of dietary calcium intake and body fat with hypertension in Indian adolescents

Kajale Neha Ekbote Veena Khadilkar Vaman Mughal Zulf Chiplonkar Shashi Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India; ²Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p52

Somatic COL1A1 mosaicism in a newborn with osteogenesis imperfecta

Bou-Torrent Rosa Iglesias Estibaliz Gimenez-Roca Clara Mensa-Vilaro Anna Yague Jordi Anton Jordi Arostegui Juan I Gonzalez-Roca Eva

¹Hospital Sant Joan de Déu, Barcelona, Spain; ²Hospital Clinic, Barcelona, Spain.

ba0004p53

Vitamin D overdose: Poor dosage guidelines for babies?

Peeva Daniela Jacobs Benjamin

Royal National Orthopaedic Hospital, London, UK.

ba0004p54

Abstract unavailable

ba0004p55

Abnormal functional responses of osteoblasts to leptin in adolescent idiopathic scoliosis

Tam Elisa Man Shan Wang Zhiwei Lee Wayne Tang Shengping Kar-Hing Yeung Tsz-Ping Lam Ng Bobby Kin Wah Cheng Jack Chun Yiu

¹Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²Department of Pediatric Orthopedics, Shenzhen Children’s Hospital, Shenzhen, China; ³Oral Maxillofacial Surgery and Dental Unit, Prince of Wales Hospital, Hong Kong, Hong Kong; ⁴Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University, Hong Kong, Hong Kong.

ba0004p56

Fractures in infants - a population-based study over 15 years in Helsinki, Finland

Ryhanen Hilkka Toiviainen-Salo Sanna Tupola Sarimari Makitie Outi Kallio Pentti E Mayranpaa Mervi

¹Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; ²Helsinki Medical Imaging Center, Helsinki, Finland; ³Folkhälsan Institute of Genetics, Helsinki, Finland.

ba0004p57

Music therapy as an avenue to promote healthy eating, exercise and bone health in children

Satoko Mori-Inoue Ilich Jasminka Z

Florida State University, Tallahassee, FL, USA.

ba0004p58

Vibration treatment can enhance the bioactive response of osteoblasts to vitamin D in adolescent idiopathic scoliosis patients

Zhang Jiajun Lee WayneY W Shi Benlong Tam Elisa M S Chen Huanxiong Lee Simon K M Ng Bobby K W Cheng Jack C Y Lam Tsz Ping

¹Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University, Hong Kong, Hong Kong; ³Lee Hysan Clinical Research Laboratories, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ⁴Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, NanJing, China.

ba0004p59

Comparing two scanning protocols for high-resolution peripheral quantitative computed tomography for bone quality assessment in young subjects

Cheuk Ka Yee Zhang Jiajun Tsang Echo Yu Fiona Hung Vivian Tam Elisa M S Lam Tsz Ping Lee Simon K M Ng Bobby K W Cheng Jack C Y

¹Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University, Hong Kong, Hong Kong; ³Lee Hysan Clinical Research Laboratories, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

ba0004p60

Association of vitamin D concentrations with 7-Dehydrocholesterol Reductase in school children in a sun-rich, semi-rural setting in Western Maharashtra, India

Mandlik Rubina Kajale Neha Chiplonkar Shashi Patwardhan Vivek Ekbote Veena Khadilkar Vaman Mughal Zulf Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India; ²Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p61

Association of dental and skeletal fluorosis with calcium intake and vitamin D concentrations in adolescents from a region endemic for fluorosis

Kajale Neha Patel Prerna Patel Pinal Patel Ashish Yagnik Bhrugu Mandlik Rubina Patwardhan Vivek Khadilkar Vaman Chiplonkar Shashi Mughal Zulf Joshi Priscilla Phanse-Gupte Supriya Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India; ²Department of Biotechnology, Hemchandrachyarya North Gujarat University, Patan, India; ³Maharaja Sayajirao University, Vadodara, India; ⁴Department of Radiodiagnosis and Imaging, bharati vidyapeeth, Pune, India; ⁵Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p62

Dietary calcium intake influences the relationship between serum 25 hydroxyvitamin D concentrations and Parathyroid hormone

Mandlik Rubina Patel Prerna Patel Pinal Patel Ashish Phanse-Gupte Supriya Kajale Neha Khadikar Vaman Chiplonkar Shashi Patwardhan Vivek Mughal Zulf Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India; ²Department of Biotechnology, Hemchandracharya North Gujarat University, Patan, India; ³Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p63

Peripubertal bone quality and density profile of Chinese adolescents in Hong Kong

Cheuk Ka Yee Cheung Franco Lee WayneY W Hung Vivian Tam Elisa Lam Tsz Ping Ng Bobby K W Lee Simon K M Cheng Jack C Y

¹Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University, Hong Kong, Hong Kong; ³Lee Hysan Clinical Research Laboratories, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

ba0004p64

Results of a specialized rehabilitation approach in osteogenesis imperfecta

Semler Oliver Hoyer-Kuhn Heike Stark Christina Schoenau Eckhard

Chilldren’s Hospital, University of Cologne, Cologne, Germany.

ba0004p65

Challenges in the management of hip dislocation a patient with Prader Willi syndrome

Eren Abdullah Cebeci Ayse Nurcan Kaymakcalan Hande Abay Burak

Istanbul Bilim University, Istanbul, Turkey.

ba0004p66

McCune-Albright Syndrome in three patients, clinical correlation and spectrum of the disease

Lammoglia Juan Mejia Liliana Boric Angelica

¹instituto de Ortopedia Infantil, Bogota, Colombia; ²Pediatric Fundacion Clinica Infantil Club Noel, Cali, Colombia; ³INstituto de INvestigacion Materno INfantil, Santiago, Chile.

ba0004p67

Body composition and vertebral changes in children with osteogenesis imperfecta -- effect of risedronate

Bishop Nick Ahmed Faisal Shaw Nick

¹University of Sheffield, Sheffield, UK; ²University of Glasgow, Glasgow, UK; ³Birmingham Children’s Hospital, Birmingham, UK; ⁴Sheffield Children’s Hospital, Sheffield, UK; ⁵Yorkhill Children’s Hospital, Glasgow, UK.

ba0004p68

A pilot study to evaluate the effectiveness of a group circuit therapy programme for children with osteogenesis imperfecta

Pullen Deirdre Mills Lisa Burren Christine

University Hospital Bristol NHS Foundation Trust, Bristol, UK.

ba0004p69

Ultrasonographic assessment of the skeletal development of the proximal tibia epiphysis, the proximal femur and the distal femur epiphysis in premature and mature newborns

Windschall Daniel Pommerenke Michael Rimsl Theresa Haase Roland

¹Department of Pediatrics, Asklepios Hospital Weissenfels, Weissenfels, Germany; ²University of Applied Sciences Ansbach, Ansbach, Germany; ³Department for Neonatology, University of Halle Wittenberg, Halle (Saale), Germany.

ba0004p70

Muscle and bone impairment in children with Marfan syndrome: correlation with age and FBN1 genotype

Haine Elsa Tauber Maithe Van Kien Philippe Khau Auriol Francoise Gennero Isabelle Julia Sophie Dulac Yves Salles Jean-Pierre Edouard Thomas

¹Endocrine, Bone Diseases, and Genetics Unit, Children’s Hospital, Toulouse University Hospital, Toulouse, France; ²INSERM UMR 1043, Centre of Pathophysiology of Toulouse Purpan (CPTP), University of Toulouse Paul Sabatier, Toulouse, France; ³Medical Genetics Unit, Nîmes University Hospital, CHU Carémeau, Nimes, France; ⁴Pediatric Clinical Investigation Center, Children’s Hospital, Toulouse University Hospital, Toulouse, France; ⁵Biochemical Laboratory, Institut Fédératif de Biologie, Toulouse University Hospital, Toulouse, France; ⁶Genetics Unit, Toulouse University Hospital, Toulouse, France; ⁷Cardiology Unit, Children’s Hospital, Toulouse University Hospital, Toulouse, France.

ba0004p71

Vitamin D status in young women with anorexia nervosa during intensive weight gain therapy

Svedlund Anna Tubic Bojan Pettersson Cecilia Magnusson Per Diana Swolin-Eide

¹Department of Pediatrics, Sahlgrenska Academy, Gothenburg University, The Queen Silvia Children’s Hospital, Gothenburg, Sweden; ²Department of Clinical Chemistry, Linköping University, Linköping, Sweden.

ba0004p72

Long-term outcomes of surgical treatment for craniofacial fibrous dysplasia

Boyce Alison Burke Andrea Peck Carolee Cutler Dufresne Craig Collins Michael

¹National Institutes of Health, Bethesda, MD, USA; ²Children’s National Health System, Washington, D.C., USA; ³SouthEast Eye Specialists, PLLC, Knoxville, TN, USA; ⁴Georgetown University and Medical Center, Washington, D.C., USA.

ba0004p73

A case of resistant hypophosphataemic rickets

Awogbemi Olumoyin Safdar Asimah McEnaney Rachel Mahmood Nasim Donne Adam Weber Astrid Dharmaraj Poonam

¹Alder Hey Children’s Hospital, Liverpool, UK; ²School of Medicine, University of Liverpool, Liverpool, UK.

ba0004p74

To predict curve progression in newly diagnosed AIS girls -- how good can bone mineral density do?

Yip Benjamin Hon Kei Yu Fiona Wai Ping Hung Vivian Wing Yin Tam Elisa Man Shan Lam Tsz Ping Qin Lin Ng Bobby Kin Wah Cheng Jack Chun Yiu

¹Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University, Hong Kong, Hong Kong; ³School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong

ba0004p75

Bone quality in severe adolescent idiopathic scoliosis -- quantitative computed tomography of lumbar spine vs high-resolution peripheral quantitative computed tomography of the distal radius: a pilot study

Yu Fiona Wai Ping Shi Lin Wang Defeng Hung Vivian Wing Yin Choy Wing Yee Hui Steve Cheuk Ngai Lee Pak Yin Tam Elisa Man Shan Lam Tsz Ping Qin Lin Ng Bobby Kin Wah Chu Winnie Chiu Wing Griffith James Cheng Jack Chun Yiu

¹Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²Department of Orthopaedics and Traumatology, Bone Quality and Health Centre, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ³Deartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong; ⁴Department of Imaging & Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

ba0004p76

Vertebral fractures in children affected by chronic recurrent multifocal osteomyelitis: case reports and therapy response

Vai Silvia Corona Fabrizia Broggi Francesca Petaccia Antonella Bianchi Maria Luisa

¹Experimental Laboratory for Children’s Bone Metabolismo Research, Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS, Milano, Italy; ²Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico, Milano, Italy.

ba0004p77

Bone metabolism in children and adolescents with newly diagnosed acute lymphoblastic leukemia

Vai Silvia Minghetti Sara Broggi Francesca Scicchitano Barbara Sala Alessandra Corso Rocco Bianchi Maria Luisa

¹Experimental Laboratory for Children’s Bone Metabolism Research, Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS, Milano, Italy; ²Department of Pediatrics, Azienda Ospedaliera S. Gerardo, University of Milano Bicocca, Monza, Italy; ³Department of Radiology, Azienda Ospedaliera S. Gerardo, University of Milano Bicocca, Monza, Italy.

ba0004p78

Nonbacterial osteitis: Is there any mismatch in the pathophysiology of osteoblasts or osteoclasts?

Singh Delila Pozza Susanne Bechtold-Dalla Gesell Isabella Susanne Schmidt Heinrich Jansson Annette

¹Dr. von Haunersches Kinderspital, Ludwig-Maximilians-University, Munich, Germany; ²Department of Orthopedic Surgery, Physical Medicine and Rehabilitation, Ludwig-Maximilians-University, Munich, Germany.

ba0004p79

Ibandronate in the treatment of pediatric osteoporosis

Kutilek Stepan Plasilova Ivana Langer Jan

¹Department of Pediatrics, Pardubice Hospital, Pardubice, Czech Republic; ²Department of Pediatrics, Klatovy Hospital, Klatovy, Czech Republic; ³Department of Pediatrics, First Medical Faculty, Charles University, Prague, Czech Republic.

ba0004p80

Liver growth hormone receptor signaling in chronic kidney disease related growth retardation: the role of suppressor of cytokine signaling 2

Hilal Rawan Abu Assadi Mohammad Hani Chen Yu Medrano Juan Rabkin Ralph Segev Yael Landau Daniel

¹Shraga Segal Department of Microbiology and Immunology1, Beer Sheva, Israel; ²Departments of Pediatrics, Beer Sheva, Israel; ³Ben Gurion University of the Negev, Beer Sheva, Israel; ⁴Department of Medicine, Stanford University, Stanford,California, USA; ⁵Research Service, Veterans Affairs Health Care System, Palo Alto, California, USA; ⁶Department Animal Science, University California, Davis, California, USA.

ba0004p81

Relationships among 25-hydroxyvitamin D, Parathyroid Hormone, and bone turnover markers in Chinese children

Han Xiao Hui-feng Zhang Xue Yan Shan-shan Wu

The Second Hospital of Hebei Medical University, Shijiazhuang, China.

ba0004p82

RANKL, OPG, Dkk1 in Duchenne muscular dystrophy

Broggi Francesca Vai Silvia Morandi Lucia Gorni Ksenija D'Angelo Grazia Pane Marika Bianchi Maria Luisa

¹Experimental Laboratory for Children’s Bone Metabolism Research, Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS, Milano, Italy; ²Unità Operativa Malattie Neuromuscolari, Istituto Nazionale Neurologico C. Besta IRCCS, Milano, Italy; ³Centro Clinico Nemo, Ospedale Niguarda, Milano, Italy; ⁴Istituto Medea IRCCS, La Nostra Famiglia, Bosisio Parini (LC), Italy; ⁵Dipartimento Neurologia Pediatrica, Policlinico Universitario ‘Agostino Gemelli’ Università Cattolica, Roma, Italy.

ba0004p83

Different causes of infantile hypercalcemia

Kutilek Stepan Plasilova Ivana Gut Josef Konrad Martin Schlingman Karl P Machata-Hanulikova Kristyna Teterova-Cerna Hana

¹Department of Pediatrics, Pardubice Hospital, Pardubice, Czech Republic; ²Department of Pediatrics, Klatovy Hospital, Klatovy, Czech Republic; ³Department of Pediatrics, Ceska Lipa Hospital, Ceska Lipa, Czech Republic; ⁴Department of Pediatrics, University Children’s Hospital Münster, Münster, Germany.

ba0004p84

Comparison of three detection assays of serum 25(OH) D

Wu Shanshan Zhang Huifeng Han Xiao

The Second Hospital of Hebei Medicine University, Shijiazhuang, China.

ba0004p85

Caries intensity and bone mineral density in children living in fluorine deficient region

Povoroznyuk Vladyslav Zadorozhna Iryna Balatska Nataliya

¹D.F. Chebotarev Institute of Gerontology NAMS Ukraine, Kyiv, Ukraine; ²Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.

ba0004p86

Influence of vitamin D deficiency on the bone mineral density in schoolchildren

Povoroznyuk Vladyslav Balatska Nataliya Tyazhka Olga Budnik Tetiana Kubey Inga Haliyash Nataliia

¹D.F. Chebotarev Institute of Gerontology NAMS Ukraine, Kyiv, Ukraine; ²Bogomolets National Medical University, Kyiv, Ukraine; ³Lugansk State Medical University, Lugansk, Ukraine; ⁴I.Y. Horbachevsky Ternopil State Medical University, Ternolpil, Ukraine.

ba0004p87

Vitamin D and bone health: A practical clinical guideline for management in children and young people in the UK

Thurston Anne Bowring Claire Shaw Nick Arundel Paul

¹National Osteoporosis Society, Camerton, Bath and North East Somerset, UK; ²Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK; ³Sheffield Children’s NHS Foundation Trust, Sheffield, UK.

ba0004p88

Bone mineral density in solid cancer survivors: a cross sectional long-term follow-up study. A preliminary report

Latoch Eryk Katarzyna Muszynska-Roslan Kaminski Marcin Jakub Panasiuk Anna Sawicka-Zukowska Malgorzata Konstantynowicz Jerzy Krawczuk-Rybak Maryna

¹Department of Pediatric Oncology and Hematology, Medical University of Bialystok, Bialystok, Poland; ²Student’s Scientific Society by the Department of Pediatric Oncology and Hematology, Medical University of Bialystok, Bialystok, Poland; ³Department of Pediatrics and Developmental Disorders, Medical University of Bialystok, Bialystok, Poland.

ba0004p89

Longitudinal bone development in patients with classical congenital adrenal hyperplasia: data using peripheral quantitative computed tomography

Bechtold Susanne Duman Leyla Weissenbacher Claudia Roeb Julia Pozza Robert Dalla Schmidt Heinrich

University Children’s Hospital, Munich, Germany.

ba0004p90

Changes in the concentration of vitamin D in the course of intensive treatment of acute lymphoblastic leukemia. A preliminary data

Muszynska-Roslan Katarzyna Latoch Eryk Panasiuk Anna Sawicka-Zukowska Malgorzata Krawczuk-Rybak Maryna

Department of Pediatric Oncology and Hematology, Medical University of Bialystok, Bialystok, Poland.

ba0004p91

Risedronate in the treatment of children with osteogenesis imperfecta: retrospective review of practice and outcomes at a large paediatric metabolic bone unit

Lawrence Neil Bishop Nick Arundel Paul

¹The University of Sheffield, Sheffield, UK; ²Sheffield Children’s Hospital, Sheffield, UK.

ba0004p92

Improving low bone mass in girls with adolescent idiopathic scoliosis (AIS) using calcium and vitamin D supplementation - a randomized controlled trial

Lam Tsz Ping Yip Benjamin Hon Kei Yu Fiona Wai Ping Tsang Echo Ka Ling To Kenneth Kin Wah Lee Yuk Wai Wong Lyn Lee Ning Lee Kwong Man Ng Bobby Kin Wah Cheng Jack Chun Yiu

¹Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong; ²School of Pharmacy, The Chinese University of Hong Kong, Shatin, Hong Kong; ³Lee Hysan Clinical Research Laboratories, The Chinese University of Hong Kong, Shatin, Hong Kong.

ba0004p93

Effects of different socioeconomic conditions on bone mineral density in healthy Turkish female university students; relation with vitamin D status

Ersoy Betul Kizilay Deniz Ozalp Gumuser Gul Taneli Fatma

¹Faculty of Medicine, Department of Pediatric Endocrinology, Celal Bayar University, Manisa, Turkey; ²Faculty of Medicine, Department of Nuclear Medicine, Celal Bayar University, Manisa, Turkey; ³Faculty of Medicine, Department of Biochemistry, Celal Bayar University, Manisa, Turkey.

ba0004p94

Osteomyelitis and septic arthritis in children: first data from the EUCLIDS network

Zenz Werner Trobisch Andreas Klobassa Daniela Binder Alexander Sperl Matthias Martinon-Torres Federico Rivero Irene Carrol Enitan D Paulus Stephane Kalifa Bojang Anderson Suzanne Schlapbach Luregn Emonts Marieke van der Flier Michiel de Groot Ronald Boeddha Navin Herberg Jethro Agapow Paul Levin Michael -on behalf of EUCLIDS consortium

¹Department of General Pediatrics, University Clinic of Pediatrics and Adolescence Medicine, Medical University Graz, Graz, Austria; ²Department of Pediatric Orthopaedics, Medical University of Graz, Graz, Austria; ³Translational Pediatrics and Infectious Diseases Section, Pediatrics Department, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain; ⁴Department Clinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection and Global Health, Liverpool, UK; ⁵Paediatric Infectious Diseases, Alder Hey Children’s Hospital, Liverpool, UK; ⁶Deparment of Paediatrics, Medical Research Council Unit, Banjul, Gambia; ⁷University Children’s Hospital Bern, University of Bern, Bern, Switzerland; ⁸Paediatric Critical Care Research Group, University of Queensland, St. Lucia, Australia; ⁹Great North Children’s Hospital, Newcastle upon Tyne Hospitals Foundation Trust, Newcastle upon Tyne, UK; ¹⁰Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK; ¹¹Department of Pediatric Infectious Diseases and Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmengen, The Netherlands; ¹²Divisions of Pediatric Infectious Diseases & Immunology, Paediatric Intensive Care University Medical Center, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands; ¹³Section of Paediatrics, Division of Infectious Diseases, Department of Medicine, Imperial College London, London, UK; ¹⁴Department of Genomics of Common Diseases, Imperial College London, London, UK, ¹⁵FP7, GA#279185, http://www.euclids-project.eu, UK.

ba0004p95

Bone health among boys with Duchenne muscular dystrophy before initiation of glucocorticoids

Tung Joanna Yuet-ling Chan Sophelia Hoi-shan Cheung Pik-to

The Department of Paediatric and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong.

ba0004p96

Dysosteosclerosis from a unique mutation in SLC29A3

Turan Serap Mumm Steven Gottesman Gary S Abali Saygin Serpil Bas Atay Zeynep William H McAlister Whyte Michael P *Dr. Turan and Dr. Mumm contributed equally to this work

¹Department of Pediatric Endocrinology, Marmara University, Istanbul, Turkey; ²Center for Metabolic Bone Disease and Molecular Research, Shriners Hospital for Children, St Louis, MO, USA; ³Division of Bone and Mineral Diseases, Washington University School of Medicine, St Louis, MO, USA; ⁴Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.

ba0004p97

Clinical predictors of low bone mineral density in children with juvenile idiopathic arthritis

Kostik Mikhail Larionova Valentina Scheplyagina Larisa

¹Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russia; ²Turner’s Scientific and Research Institute for Children’s Orthopedics, Saint-Petersburg, Russia; ³Moscow Scientific and Research Clinical Institute named M.F. Vladimirskiy, Moscow, Russia.

ba0004p98

The role of vitamin D in growth physiology in early-aged and preschool children

Scheplyagina Larisa

Moscow Scientific and Research Clinical Institute named M.F. Vladimirskiy, Moscow, Russia.

ba0004p99

Secondary osteoporosis in boys with Alagille syndrome -- case report

Jakubowska-Pietkiewicz Elzbieta Smiechowicz Ewa Chlebna-Sokol Danuta

Medical University of Lodz, Lodz, Poland.

ba0004p100

X-linked spinal muscular atrophy caused by de novo c.1731C>T substitution in the UBA1 gene

Jedrzejowska Maria Kostera-Pruszczyk Anna Jakubowska-Pietkiewicz Elzbieta

¹Polish Academy of Sciences, Warsaw, Poland; ²Medical University of Lodz, Lodz, Poland; ³Medical University of Warsaw, Warsaw, Poland.

ba0004p101

Bone robusticity in two distinct skeletal dysplasias: an evaluation of the second metacarpal, a surrogate for bone strength

Marino Josephine Jepsen Karl Carter Erin Raggio Cathleen

¹Hospital for Special Surgery, New York, NY, USA; ²University of Michigan, Ann Arbor, MI, USA.

ba0004p102

Gait assessment in children with childhood hypophosphatasia: impairments in muscle strength and physical function

Phillips Dawn Griffin Donna Przybylski Tracy Morrison Erica Reeves Amy Vallee Marc Fujita Kenji Madson Katherine Whyte Michael

¹UNC Division of Physical Therapy, Chapel Hill, NC, USA; ²Shriners Hospital for Children, St. Louis, MO, USA; ³Alexion Pharmaceuticals, Cheshire, CT, USA.

ba0004p103

Effect of intravenous pamidronate in the treatment of skin calcinosis in the course of juvenile dermatomyositis -- a story half-told

Abramowicz Pawel Dobrenko Elzbieta Abramowicz Magdalena Konstantynowicz Jerzy

Department of Pediatrics and Developmental Disorders, Medical University of Bialystok, Bialystok, Poland.

ba0004p104

Refractory hypercalcaemia of malignancy: responsiveness to Denosumab and Zoledronate

Giri Dinesh Ramakrishnan Renuka Hayden James Brook Lynda Das Urmi Mughal M Zulf Selby Peter Dharmaraj Poonam Senniappan Senthil

¹Alder Hey Children’s Hospital NHS Trust, Liverpool, UK; ²Royal Manchester Children’s Hospital, Manchester, UK; ³Manchester Royl Infirmary, Manchester, UK.

ba0004p105

Metatropic dysplasia is associated with increased fracture risk and increased markers of bone turnover

Bober Michael Duker Angela Carney Megan Ditro Colleen Rogers Kenneth Mackenzie William

A.I. duPont Hospital for Children, Wilmington, DE, USA.

ba0004p106

Bone mineral density in Pelizaeus Merzbacher disease

Kecskemethy Heidi Hobson Grace Theodore Harcke H

¹Nemours/A.I.duPont Hospital for Children, Wilmington, DE, USA; ²University of Delaware, Newark, DE, USA; ³Thomas Jefferson University, Philadelphia, PA, USA.

ba0004p107

Unique occurrence of long bone fragility with cranial hyperostosis: Searching for the genetic culprit

Raimann Adalbert Wintergerst Uwe Roschger Paul Stelzl Rainer Biedermann Rainer Rasse Michael Fratzl-Zelman Nadja Laccone Franco Klaushofer Klaus Haeusler Gabriele

¹Medical University of Vienna, Vienna, Austria; ²Krankenhaus St. Josef Braunau, Braunau, Austria; ³Medical University of Innsbruck, Innsbruck, Austria; ⁴Ludwig Boltzmann Institute of Osteology at Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria.

ba0004p108

Effects of inorganic phosphate and FGF23 on C2C12 myoblast cells

Raimann Adalbert Dangl Alexander Sagmeister Susanne Greber-Platzer Susanne Haeusler Gabriele

Medical University of Vienna, Vienna, Austria.

ba0004p109

Abstract unavailable

ba0004p110

Is groupwork an effective way to improve transition for young people with osteogenesis imperfecta? A pilot study

Ball Suzanne Mitchell Ryan

Birmingham Children’s Hospital, Birmingham, UK.

ba0004p111

Type V osteogenesis imperfecta: confirmation of highly characteristic radiographic findings in early infancy

Arundel Paul Offiah Amaka Bishop Nick Ehtisham Sarah

¹Sheffield Children’s NHS Foundation Trust, Sheffield, Yorkshire, UK; ²University of Sheffield, Sheffield, UK; ³Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p112

Comparison of cost benefits and efficacy of Zoledronic acid and Pamidronate in the treatment of osteogenesis imperfecta in children

Saraff Vrinda Sahota Jaskiran Crabtree Nicola Shaw Nick Hogler Wolfgang

Birmingham Children’s Hospital, Birmingham, UK.

ba0004p113

Influence of pubertal development and body composition on bone mass accrual in apparently healthy school children aged 6-17 years

Dabas Aashima Khadgawat Rajesh Marwaha R K Mehan N Sastry A Badra K

¹All India Institute of Medical Science, New Delhi, India; ²Institute of Nuclear Medicine and allied Sciences, New Delhi, India; ³Sur Medical College, New Delhi, India.

ba0004p114

Vitamin D and bone mineral density in children with Duchenne muscular dystrophy relation to fractures and ambulation status

Buckner Jason Bowden Sasigarn

¹Nationwide Children’s Hospital, Columbus, OH, USA; ²Ohio State University, Columbus, OH, USA.

ba0004p115

Osteopetrosis with uncommon final height: can only local IGF1 hold normal growth during pubertal spurt?

Milani Soraya Sader Paula Francisco Jose Liberatore Jr Raphael Martinelli Jr Carlos Eduardo

Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto/Sao Paulo, Brazil.

ba0004p116

Familial hypocalciuric hypercalcemia in two Chinese families -- common and uncommon features

Lee Lai-Ka Yau Ho-Chung Yuen Liz

¹The Chinese University of Hong Kong, Hong Kong, Hong Kong; ²The Prince of Wales Hospital, Hong Kong, Hong Kong.

ba0004p117

Changes in total body and regional bone mass in relation to body composition in children with osteogenesis imperfecta treated with pamidronate

Sritharan Shironisha Gopal-Kothandapani Jaya Sujatha Bishop Nick Dimitri Paul

¹The University of Sheffield, Sheffield, South Yorkshire, UK; ²Sheffield Children’s NHS Foundation Trust, Sheffield, South Yorkshire, UK.

ba0004p118

Burden of disease in children with hypophosphatasia: results from patient-reported surveys

Weber Thomas Sawyer Eileen Moseley Scott Odrljin Tatjana Kishnani Priya

¹Duke University Medical Center, Durham, NC, USA; ²Alexion Pharmaceuticals, Cheshire, CT, USA.

ba0004p119

Fracture incidence and bisphosphonate therapy in boys with Duchenne Muscular Dystrophy

Crabtree Nicola Hogler Wolfgang Sahota Jaskiran Chapman Dee Walford Jacky Roper Helen Willis Tracy Shaw Nicholas

¹Birmingham Children’s Hospital, Birmingham, UK; ²Heart of England Hospital, Birmingham, UK; ³Robert Jones and Agnes Hunt Hospital, Oswestry, UK.

ba0004p120

A case of osteogenesis imperfecta mimicking the features of mucopolysaccharidosis IVA

Gul Yesiltepe Mutlu Aydin Hatip Kirmizibekmez Heves Gokmeydan Eylem

¹Department of Pediatric Endocrinology, Zeynep Kamil Woman and Children’s DiseasesTraining and Research Hospital, Istanbul, Turkey; ²Center of Genetics Diagnosis, Zeynep Kamil Woman and Children’s Diseases Training and Research Hospital, Istanbul, Turkey; ³Center of Genetics Diagnosis, Dr. Lutfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey.

ba0004p121

Phalangeal microgeodic disease: A rare cause of painful swollen toes

Govindan Ranjith Green Ruth Dyankova-Peeva Daniela Keen Richard Jacobs Benjamin

¹Royal National Orthopaedic Hospital, London, UK; ²Hillingdon Hospital, London, UK.

ba0004p122

Does the introduction of vertebral fracture assessment change clinical practice?

Chapman Dee Walford Jacky Shaw Nicholas Hogler Wolfgang Crabtree Nicola

Birmingham Children’s Hosptial, Birmingham, UK.

ba0004p123

Bisphosphonate treatment and the characteristics of femoral fractures in children with osteogenesis imperfecta

Vuorimies Ilkka Mayranpaa Mervi Valta Helena Kroger Heikki Toiviainen-Salo Sanna Makitie Outi

¹Folkhälsan Institute of Genetics, Helsinki, Finland; ²Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; ³Department of Pediatric Radiology, Helsinki Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; ⁴Bone and Cartilage Research Unit, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.

ba0004p124

Vitamin D status of gastrostomy-fed children with special needs

Kuter Hayley Das Geeta Mughal M Zulf

Central Manchester Children’s Hospital, Manchester, UK.

ba0004p125

Low bone mass in children with epidermolysis bullosa

Katharina Ude-Schoder

EB Haus Austria, University Clinic of Dermatology, Salzburg, Austria.

ba0004p126

The outcomes of a standardized approach to managing metabolic bone disease of prematurity

Chin Lit Kim Doan John Teoh Yvonne Sui Lien Stewart Alice Forrest Peter Simm Peter J

¹Royal Children’s Hospital, Melbourne, Victoria, Australia; ²Deparment of Paediatrics, Dandenong Hospital, Melbourne, Victoria, Australia; ³Department of Neonatology, Monash Children’s, Melbourne, Victoria, Australia; ⁴Department of Endocrinology and Diabetes, Monash Children’s, Melbourne, Victoria, Australia; ⁵Murdoch Childrens Research Institute, Melbourne, Victoria, Australia.

ba0004p127

Patients treated with anti-epileptic drugs have a higher rate of fracture and impaired bone and muscle development compared with controls: results from a pilot study

Simm Peter J Seah Sebastian Mackay Mark Freeman Jeremy Petty Sandra J Wark John D

¹Deparment of Endocrinology and Diabetes, Royal Children’s Hospital, Melbourne, Victoria, Australia; ²Murdoch Childrens Research Institute, Melbourne, Victoria, Australia; ³Deparment of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia; ⁴Deparment of Neurology, Royal Children’s Hospital, Melbourne, Victoria, Australia; ⁵Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, Victoria, Australia; ⁶Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia; ⁷Bone and Mineral Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

ba0004p128

Cortical area and volumetric density during pubertal growth: longitudinal analysis in black and white South African adolescent males

Schoenbuchner Simon Ward Kate Norris Shane Prentice Ann Pettifor John

¹MRC Human Nutrition Research, Cambridge, UK; ²MRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg, South Africa.

ba0004p129

Chronic recurrent multifocal osteomyelitis: the value of whole-body MRI in a series of 34 children

Jacobs Benjamin Brown Mathew Guha Ananya Alexandrou Dion Paul O'Donnell Keen Richard

Royal National Orthopaedic Hospital, Stanmore, London, UK.

ba0004p130

Association between serum 25-hydroxyvitamin D and incidence of infections in 6--12 years old children in a semi-rural setting in Western Maharashtra, India

Mandlik Rubina Kajale Neha Chiplonkar Shashi Patwardhan Vivek Phanse-Gupte Supriya Khadilkar Vaman Mughal Zulf Khadilkar Anuradha

¹Growth and Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India; ²Royal Manchester Children’s Hospital, Manchester, UK.

ba0004p131

Bone structural characteristics and response to bisphosphonate treatment in children with Hajdu--Cheney syndrome

Sakka Sophia RachelI Gafni Clarke Bart Rauch Frank Hogler Wolfgang

¹Department of Paediatric Endocrinology and Diabetes, Birmingham Children’s Hospital, Birmingham, West Midlands, UK; ²Craniofacial and Skeletal Diseases Branch, NIDCR National Institutes of Health, Bethesda, Maryland, USA; ³Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA; ⁴Genetics Unit, Shriners Hospital for Children and McGill University, Montreal, Quebec, Canada.

ba0004p132

Fibrodysplasia ossificans progressiva: disabling but now treatable

Keen Richard Jacobs Benjamin Mughal M Zulf

Royal National Orthopaedic Hospital, Stanmore, London, UK.

ba0004p133

Associations of 25-hydroxyvitamin D with major components of metabolic syndrome in children

Challa Anna Evagelidou Eleni Siomou Ekaterini Tzallas Alexandros Giapros Vasileios

¹Child Health Department, University of Ioannina, Ioannina, Greece; ²Department of Computer Engineering, School of Applied Technology, Arta, Greece; ³Neonatology Deparment, University of Ioannina, Ioannina, Greece.

ba0004p134

Chronic recurrent multifocal osteomyelitis in children: a new, MRI-based method of quantifying inflammation in the bone

Alexandrou Dionysios Jacobs Benjamin Paul O'Donnell Hargunani Rikin Guha Ananya Roettger Diana Kubassova Olga

¹The Royal National Orthopaedic Hospital, Stanmore, UK; ²The Moorfields Eye Hospital, London, UK; ³The Portland Hospital for Women and Children, London, UK; ⁴Image Analysis UK, London, UK.

ba0004p135

A modified performance-oriented mobility assessment tool for assessing clinically relevant gait impairments and change in children with hypophosphatasia: development and validation

Phillips Dawn Griffin Donna Przybylski Tracy Morrison Erica Reeves Amy Vallee Marc Fujita Kenji Madson Katherine Whyte Michael

¹UNC Division of Physical Therapy, Chapel Hill, North Carolina, USA; ²Shriners Hospital for Children, St Louis, Missouri, USA; ³Alexion Pharmaceuticals, Cheshire, Connecticut, USA.

ba0004p136

A slow and difficult diagnosis of a child with chronic recurrent multifocal osteomyelitis

Guha Ananya Brown Mathew Green Ruth Keen Richard Calder Peter Jacobs Benjamin

Royal National Orthopaedic Hospital, Stanmore, London, UK.

ba0004p137

In-depth phenotyping including analyses of skin connective tissue in osteogenesis imperfecta

Balasubramanian Meena Bishop Nick

¹Sheffield Children’s NHS Foundation Trust, Sheffield, UK; ²Academic Unit of Child Health, University of Sheffield, Sheffield, UK.

ba0004p138

Abstract unavailable

ba0004p139

Rickets in two patients pediatrics

de Beldjenna Liliana Mejia Lammoglia Juan Javier Rengifo Anuar

¹Fundation clinic Infantil Club Noel - University Libre, Corserinsa, Cali-Valle del Cauca, Colombia; ²Institut of Orthopedic Rosselvet, Bogota, Colombia; ³Universiry Libre-Fundation CLinic Infantil Club Noel, Cali-Valle del Cauca, Colombia.

ba0004p140

Persistence of musculoskeletal abnormalities in children and adolescents with inflammatory bowel disease: a prospective longitudinal study

S McCarrison Mason A SC Wong Shepherd S P McGrogan Russell R SF Ahmed

¹Developmental Endocrinology Research Group, University of Glasgow, Royal Hospital for Sick Children, Glasgow, UK; ²Department of Paediatric Gastroenterology, Royal Hospital for Sick Children, Glasgow, UK.

ba0004p141

The mechanical multi-stimulation for musculoskeletal disease

Park Ji Hyung Cho Seungkwan Seo Dong-Hyun Hwang Dong-Hyun Han Tae-Young Kim Han Sung

¹Yonsei-Fraunhofer Medical Device Laboratory, Yonsei University, Wonju, Republic of Korea; ²Fraunhofer Institute IKTS-MD, Dresden, Germany.

ba0004p142

Low serum vitamin D levels in children treated for hematologic oncologic diseases

Sperl Daniela Krause Tobias Lackner Herwig Obermayer-Pietsch Barbara Decrinis Clare Berger Astrid Sovinz Petra Seidel Markus Schwinger Wolfgang Benesch Martin Strenger Volker Schmidt Sandrin Urban Christian E

¹Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology/Oncology, Medical University of Graz, Graz, Austria; ²Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.

ba0004p143

Hypomagnesaemia due to lead poisoning in the context of a heterozygous CLDN-16 mutation

Ramaswamy Priya Kurre Malathi Muller Dominik Dargan Paul Gevers Evelien Allgrove Jeremy

¹Royal London Hospital, London, UK; ²Royal London Hospital, London, UK; ³Charite Department of Paediatric Nephrology, Berlin, Germany; ⁴Guy’s and St Thomas’ NHS Foundation Trust, London, UK; ⁵Royal London Hospital, London, UK; ⁶Royal London Hospital, London, UK.

ba0004p144

Zoledronate as first line therapy for pediatric osteogenesis imperfecta?

Keemink Yvette van Brussel Marco Sakkers Ralph Pruijs Hans van Dijk Atty

¹University Medical Centre, Utrecht, The Netherlands; ²Wilhelmina Children’s Hospital, Utrecht, The Netherlands.

ba0004p145

Hypovitaminosis D and factors associated in healthy children aged 2--14 years old in Mexico

Chico-Barba Gabriela Huitron Gerardo Guagnelli Miguel Clark Patricia

¹Instituto Nacional de Perinatología, Mexico City, Mexico, ²Universidad Autónoma del Estado de México, Toluca, Edo. Mexico City, Mexico, ³Hospital Infantil de Mexico, Mexico City, Mexico.

ba0004p146

A severe form of cerebral palsy as a risk factor for the development of secondary osteoporosis in children

Nenadov Natasa Krasnik Rastislava Svorcan Jelena Zvekic Mikov Aleksandra Drljan Cila Demesi Radovanov Maja

¹Home ‘Veternik’, Novi Sad, Vojvodina, Serbia, ²Clinic of Child Habilitation and Rehabilitation, Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Vojvodina, Serbia, ³Special Hospital for Rheumatic Diseases Novi Sad, Novi Sad, Vojvodina, Serbia, ⁴Health Care, Novi Sad, Vojvodina, Serbia, ⁵Medical Faculty, University of Novi Sad, Novi Sad, Vojvodina, Serbia.

ba0004p147

Prevalence of vertebral fractures in survivors of childhood acute lymphoblastic leukemia

Fiscaletti Melissa Dubois Josee Miron Marie-Claude Krajinovic Maja Laverdiere Caroline Sinnett Daniel Alos Nathalie

Sainte-Justine UHC Research Cente, Montreal, Canada.

ba0004p148

Trabecular bone density decreased during 6 year observation in girls with Turner syndrome, but was not associated with fracture history

Soucek Ondrej Sumnik Zdenek Snajderova Marta Kolouskova Stanislava Lebl Jan

Department of Paediatrics, Charles University in Prague and Motol University Hospital, Prague, Czech Republic.

ba0004p149

Impaired bone mineral density in adult survivors of childhood cancer: a literature review

Pluijm Saskia Marissa den Hoed Neggers Sebastian Pieters Rob den Heuvel-Eibrink Marryvan

¹ErasmusMC, Department of Paediatric Oncology/Haematology, Rotterdam, The Netherlands; ²Princess Maxima Center for Paediatric Oncology, Utrecht, The Netherlands; ³Department of Internal Medicine, Section of Endocrinology, Rotterdam, The Netherlands.

ba0004p150

Do children with mild to moderate osteogenesis imperfecta (OI) with abdominal muscle weakness have a higher incidence of pars defects? A physiotherapy pilot

Hupin Emilie Edwards Karen Chueng Moira Allgrove Jeremy DeVile Catherine

Great Ormond Street Hospital for Children, London, UK.

ba0004p151

Syphilitic bone disease: a case report

Sukthankar Shaila Sukthankar Ashish Wright Neville Foster Anne Mughal Zulf

Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

ba0004p152

In-vivo high-resolution peripheral quantitative computer tomography assessment of skeletal microstructure in children with osteogenesis imperfecta

Digby Maria Dimitri Paul Arundel Paul Bishop Nick Paggiosi Margaret Offiah Amaka

¹University of Sheffield, Sheffield, UK; ²Sheffield Children’s Hospital, Sheffield, UK; ³Academic Unit of Child Health, Sheffield, UK; ⁴Academic Unit of Bone Metabolism, Sheffield, UK.

ba0004p153

A longitudinal, prospective, long-term registry of patients with hypophosphatasia

Kishnani Priya Langman Craig Linglart Agnes Mornet Etienne Ozono Keiichi Rockman-Greenberg Cheryl Seefried Lothar Bedrosian Camille Fujita Kenji Cole Alex Hogler Wolfgang

¹Medical Center, Duke University, Durham, NC, USA; ²Northwestern University and Lurie Children’s Hospital, Chicago, IL, USA; ³Paris-Sud University, APHP and INSERM, Paris, France; ⁴Université de Versailles, Saint Quentin en Yvelines, France; ⁵Graduate School of Medicine, Osaka University, Osaka, Japan; ⁶University of Manitoba, Winnipeg, MB, Canada; ⁷University of Würzburg, Würzburg, Germany; ⁸Alexion Pharmaceuticals, Cheshire, CT, USA; ⁹Birmingham Children’s Hospital, Birmingham, UK.

ba0004p154

Hydroxylase (CYP27B1) deficiency presenting with marked hypotonia, growth failure, hypoventilation, pulmonary hypertension and a renal proximal tubulopathy

Barton John Hayes Wesley Burren Christine

¹Department of Paediatric Endocrinology, Bristol Royal Hospital for Children, Bristol, UK; ²Department of Paediatric Nephrology, Bristol Royal Hospital for Children, Bristol, UK.

ba0004p155

Children with coeliac disease on gluten free diet have normal bone mass, geometry and muscle mass

Mackinder M SC Wong Tsiountsioura M Shepherd S Tellemer E Kyriakou A Buchanan E Edwards C SF Ahmed P McGrogan Gersimidis K

¹Department of Human Nutrition, University of Glasgow, Glasgow, UK; ²Developmental Endocrinology Research Group, Royal Hospital for Sick Children, Glasgow, UK; ³Department of Dietetic, Royal Hospital for Sick Children, Glasgow, UK; ⁴Department of Paediatric Gastroenterology, Royal Hospital for Sick Children, Glasgow, UK.

ba0004p156

Hypoxia inducible factor-1α directly induces the expression of receptor activator of nuclear factor-κB ligand in MLO-Y4 osteocytes

Baek Kyunghwa Park Hyun-jung Baek Jeong-hwa

¹Department of Pharmacology, College of Dentistry and Research Institute of Oral Science, Gangneung-Wonju National University, Gangneung, Republic of Korea; ²Department of Molecular Genetics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.

ba0004p157

Extreme, biomechanically-explained remodelling of biological femoral reconstructions in pediatric oncology

Taddei Fulvia Valente Giordano Piroddi Sabina Schileo Enrico Pitto Lorenzo Roncari Andrea Leardini Alberto Manfrini Marco

Istituto Ortopedico Rizzoli, Bologna, Italy.

ba0004p158

The usefulness of bioelectrical impedance analysis in the proper assessment of nutritional status in children and adolescents with idiopathic scoliosis

Matusik Edyta Durmala Jacek Matusik Pawel Wadolowski Karol

¹Chair and Department of Rehabilitation, School of Health Science, Medical University of Silesia, Katowice, Poland; ²Chair and Department of Pediatrics, Pediatric Endocrinology and Diabetes, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

ba0004p159

Prevalence of muscle deficits in survivors of childhood acute lymphoblastic leukemia

Veilleux Louis-Nicolas Rauch Frank Curnier Daniel Krajinovic Maja Laverdiere Caroline Sinnett Daniel Alos Nathalie

¹Sainte-Justine UHC Research Center, Montreal, Canada; ²Shriners Hospital, Montreal, Canada.

ba0004p160

Unusual adverse reaction of pamidronate: thrombophlebitis

Orbak Zerrin Kaya Avni

Ataturk University Medical Faculty, Erzurum, Turkey.

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Abstract unavailable

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Whole blood gene expression analysis in idiopathic infantile hypercalcemia due to compound heterozygous mutation in the CYP24A1 gene in an Austrian 4-month-old boy and his family

Hofer Daniela Zachhuber Verena Lindheim Lisa Munzker Julia Trummer Olivia Schweighofer Natascha Ulbing Matthias Obermayer-Pietsch Barbara

Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University Graz, Graz, Austria.

ba0004p163

Effect of vitamin D supplementation on glucose metabolism, immune function and bone turnover in children with vitamin D deficiency

N El Fakhri J McNeilly M McMillan M Le Brocq Boroujerdi M Halsey C Ahmed S F H McDevitt

¹Developmental Endocrinology, Research Group, Royal Hospital for Sick Children, Glasgow, UK; ²Department of Biochemistry, Southern General Hospital, Glasgow, UK; ³Institute of Infection, Immunity and Inflammation, Centre for Immunobiology, Glasgow, UK.

ba0004p164

Clinical masks of the tricho-rhino-phalangeal syndrome: based on the series of four cases from Poland

Matusik Pawel Forys-Dworniczak Elzbieta Kalina-Faska Barbara Januszek-Trzciakowska Aleksandra Malecka-Tendera Ewa

¹Chair and Department of Pediatrics, Pediatric Endocrinology and Diabetes, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland; ²Uppersilesian Child Health Centre, Katowice, Poland.

ba0004p165

The role of AMPK pathway in mediating the effects of metformin on mesenchymal stem cell differentiation

Chen Suet Ching Brooks Rebecca Ahmed Syed Faisal Yarwood Stephen J

¹Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK; ²Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

ba0004p166

Muscle power and force are predictors of bone microarchitecture and strength in healthy children and adolescents measured by high resolution peripheral quantitative computed tomography and jumping mechanography

Riddell Amy Solis-Trapala Ivonne Prentice Ann Ward Kate

MRC Human Nutrition Research, Cambridge, UK.

ba0004p167

Ambulatory impairment and bone status in subjects with Rett Syndrome: a 10-year longitudinal study

Caffarelli Carla Pitinca Maria Dea Tomai Francolini Valentina Hayek Joussef Nuti Ranuccio Gonnelli Stefano

¹Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy; ²Paediatrics Neuropsychiatry Unit, University of Siena, Siena, Italy.

ba0004p168

Comparison of the response to bisphosphonate treatment between acute lymphoblastic leukaemia and osteogenesis imperfecta type I

Kumaran Anitha Uday Suma Ginige Nimasari Sakka Sophia Saraff Vrinda Sahota Jaskiran Crabtree Nicola Shaw Nick Hogler Wolfgang

Birmingham Children’s Hospital, Birmingham, UK.

ba0004p169

Reduced spinal volumetric trabecular bone mineral density in adolescent girls with anorexia nervosa

Ehtisham Sarah Whittaker Jane Adams Judith Mughal Zulf

¹Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK; ²Child and Adolescent Mental Health Services, Galaxy House, Royal Manchester Children’s Hospital, Manchester, UK; ³Department of Clinical Radiology, Manchester Royal Infirmary, Manchester, UK.

ba0004p170

Bone-muscle unit assessment with pQCT in children with inflammatory bowel disease following treatment with Infliximab

Altowati Mabrouka Malik S Shepherd S P McGrogan RK Russell SF Ahmed SC Wong

¹Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK; ²Department of Has grown teleology Royal Hospital for Sick Children, Glasgow, UK.

ba0004p171

The possibilities of bone regeneration in children

Michovich Michail Glazkin Leonid Lamnev Viktor

Mogilev Regional Children’s Hospital, Mogilev, Belarus.

ba0004p172

Papilledema in a toddler: An atypical presentation of X-linked hypophosphatemic rickets

Wasserman Halley Stenger Peggy

Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.

ba0004p173

Case report of reversible cardiomyopathy secondary to 1 alpha hydroxylase deficiency

Cheung Moira Braha Nirit Beck-Nielsen Signe Brain Caroline Allgrove Jeremy

¹Great Ormond Street Hospital NHS Foundation Trust, London, UK; ²University of South Denmark, Odense, Denmark.

ba0004p174

Effect of baseline vitamin D status on serum 25(OH) D level and body composition in breastfed infants on vitamin D supplementation

Czech-Kowalska Justyna Jaworski Maciej Maksym Dorota Nowakowska-Rysz Monika Wygledowska Grazyna Pawlus Beata Zochowska Anna Kornacka Maria Dobrzanska Anna

¹Department of Neonatology and Neonatal Intensive Care, The Children’s Memorial Health Institute, Warsaw, Poland; ²Department of Biochemistry Radioimmunology and Experimental Medicine, The Children’s Memorial Health Institute, Warsaw, Poland; ³Department of Neonatology, Miedzyleski Specialist Hospital, Warsaw, Poland; ⁴Department of Neonatology, Holy Family Hospital, Warsaw, Poland; ⁵Department of Neonatology, Public Hospital, Otwock, Poland; ⁶Department of Neonatology, Warsaw Medical University Hospital, Warsaw, Poland.

ba0004p175

Evaluation of fibroblast growth factor 23 in patients with hypophosphataemic rickets

Park Julie Khan Kursheed Hatchard Lynne Ramakrishnan Renuka Senniappan Senthil Fraser William Dharmaraj Poonam

Alder Hey Children’s Hospital, Liverpool, UK.

ba0004p176

Fractures in boys with Duchenne muscular dystrophy and their relationship to age

Joseph Shuko Dunne Jennifer Di Marco Marina Shepherd Sheila Horrocks Iain SF Ahmed SC Wong

¹Paediatric Neurosciences Research Group, The Fraser of Allander Neurosciences Unit. The Royal Hospital for Sick Children, Glasgow, UK; ²Developmental Endocrinology Research Group, The Royal Hospital for Sick Children, Glasgow, UK.

ba0004p177

The precision of partial image analysis of trabecular bone microarchitecture by high-resolution magnetic resonance imaging in people with childhood-onset bone abnormalities

Chen Suet Ching Abdalrahaman Naiemh McComb Christie Foster John Ahmed Syed Faisal

¹Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK; ²Department of Clinical Physics, NHS Greater Glasgow and Clyde, Glasgow, UK.

ba0004p178

An atypical case of bone fragility and dysmorphism with an unusual and novel de novo COL1A1 mutation

Skae Mars Rauch Frank Mughal Zulf Sims Jo Davis Naomi Scott B Arundel Paul Hobson Emma

¹Department of Paediatric Endocrinology, Royal Manchester Childrens Hospital, Manchester, UK; ²Department of Paediatrics, McGill University, Shriners Hospital for Children, Montreal, Canada; ³Department of Paediatrics, Calderdale Royal Hospital, Halifax, UK; ⁴Department of Paediatric Orthopaedics, Royal Manchester Children’s Hospital, Manchester, UK; ⁵Department of Paediatric Orthopaedics, Leeds General Infirmary, Leeds, UK; ⁶Department of Metabolic Bone Disease, Sheffield Children’s NHS Foundation Trust, Sheffield, UK; ⁷Department of Clinical Genetics, Chapel Allerton Hospital, Leeds, UK.

ba0004p179

Rare diseases of bones, joints and vessels study

Forestier-Zhang Lydia Barrett Joe Wordsworth Paul Luqmani Raashid Bishop Nicholas Kassim Javaid Muhammad

¹University of Oxford, Oxford, UK; ²The University of Sheffield, Sheffield, UK.

ba0004p180

Short stature in osteogenesis imperfecta: consider alternative diagnoses

Steele Caroline Sultan Wajid Bishop Nick Ehtisham Sarah

¹Royal Manchester Children’s Hospital, Manchester, UK; ²University Hospitals of Morecambe Bay, Morecambe Bay, UK; ³Sheffield Children’s Hospital, Sheffield, UK.

ba0004p181

A case of moderate osteogenesis imperfecta with cerebral palsy spastic quadriplegia; an impossible combination, or is it?

Knowles Elizabeth

Sheffield Children’s Hospital, Sheffield, UK.

ba0004p182

Deficits of vitamin D are strongly associated with methotrexate treatment in patients with juvenile idiopathic arthritis

Goralczyk Adrian Konstantynowicz Jerzy Abramowicz Pawel Dobrenko Elzbieta Babinska-Malec Edyta

¹Department of Pediatrics & Developmental Disorders, Medical University of Bialystok, Bialystok, Poland; ²Student’s Scientific Society, Medical University of Bialystok, Bialystok, Poland.

ba0004p183

A subtrochanteric femoral stress fracture following bisphosphonate treatment in an adolescent girl

Boyce Alison Tosi Laura Gafni Rachel

¹Skeletal Clinical Studies Unit, CSDB, NIDCR, National Institutes of Health, Bethesda, MD, USA; ²Bone Health Program, Division of Orthopaedics and Sports Medicine, Children’s National Health System, Washington, DC, USA.

ba0004p184

The effect of iron chelators on bone health in patients with thalassemia

Fung Ellen Luo Nan Gildengorin Ginny Lal Ashutosh

¹UCSF Benioff Children’s Hospital Oakland, Oakland, CA, USA; ²Children’s Hospital Oakland Research Institute, Oakland, CA, USA.

ba0004p185

Cole-Carpenter syndrome

Balasubramanian Meena Bishop Nick

¹Sheffield Children’s NHS Foundation Trust, Sheffield, UK; ²Academic Unit of Child Health, University of Sheffield, Sheffield, UK.

ba0004p186

TBS increases over time in pre-teen girls

Libber J Winzenrieth R Krueger D Scarpella T Binkley N

¹University of Wisconsin Osteoporosis Clinical Research Program, Madison, WI, USA; ²R&D Department, Med-Imaps, Merignac, France; ³University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

ba0004p187

Fractures, bone mass and geometry in black and white South African children: The Birth to Twenty cohort

Thandrayen Kebashni Schoenbuchner Simon Ward Kate Micklesfield Lisa Norris Shane Prentice Ann Pettifor John

¹University of the Witwatersrand, Johannesburg, South Africa; ²University of Cambridge, Cambridge, UK.

ba0004p188

Two infants with the diagnosis of infantile hypophosphatasia: case report

Akyurek Nesibe Atabek Mehmet Emre Eklioglu Beray Selver

¹Department of Pediatric Endocrinology and Diabetes, Konya Training and Research Hospital, Meram/Konya, Turkey; ²Department of Pediatric Endocrinology and Diabetes, School of Medicine, Necmettin Erbakan University, Meram/Konya, Turkey.

ba0004p189

Bone quality and quantity in Duchenne Muscular Dystrophy patients

Del Rio Luis Winzenrieth Renaud Di Gregorio Silvana

¹Cetir Group Medic, Barcelona, Spain; ²R&D Department, Med-Imaps, Merignac, France.

ba0004p190

Evolution of bone quality and quantity in patients suffering from Duchenne Muscular Dystrophy

Del Rio Luis Di Gregorio Silvana Winzenrieth Renaud

¹Cetir Group Medic, Barcelona, Spain; ²R&D Department, Med-Imaps, Merignac, France.

ba0004p191

Low bone mineral density and fractures are prevalent in children with spinal muscular atrophy

Wasserman Halley Hornung Lindsey Stenger Peggy Rutter Meilan Wong Brenda Rybalsky Irina Khoury Jane Kalkwarf Heidi

Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.

ba0004p192

Aggravated bone density decline following symptomatic osteonecrosis in children with acute lymphoblastic leukemia

den Hoed MAH SMF Pluijm de Groot-Kruseman HA Fiocco M Hoogerbrugge P JA Leeuw MCA Bruin van der Sluis IM Bresters D MH Lequin JC Roos AJP Veerman Pieters R van den Heuvel-Eibrink MM

¹Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands; ²Dutch Childhood Oncology Group, Hague, The Netherlands; ³Princess Maxima Center, Utrecht, The Netherlands; ⁴Leiden University Medical Center, Leiden, The Netherlands; ⁵Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands; ⁶University of Groningen, Groningen, The Netherlands; ⁷University Medical Center Utrecht, Utrecht, The Netherlands; ⁸Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

ba0004p193

Results of conservative treatment in patients with phosphate diabetes

Martsyniak Stepan Guk Iurii Tamara Kinchaya-Polishchuk Zyma Andrii Stewart David G Bondariev Gennadii Pankina Olha

¹Institute of Orthopedics and Traumatology, National Academy of Medical Sciences, Kyiv, Ukraine; ²Childrens Bone and Spine Surgery, Las-Vegas, Nevada, USA.

ba0004p194

Increase of bone mineral density in patients with osteogenesis imperfecta treated with pamidronate disodium.

de Menezes Filho Hamilton Cabral de Brito Pupo Joyce de Magalhaes Velasco Bastos Paula Ae Kim Chong Bertola Debora Romeo Ito Simone Sakura dos Santos Tiago Jeronimo Setian Nuvarte Damiani Durval

Instituto da Criança – Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.

ba0004p195

Early onset cataract in an infant with activating calcium sensing receptor mutation

Ramaswamy Priya Ryalls Michael Allgrove Jeremy

¹Royal London Hospital, London, UK; ²Royal Surrey County Hospital, Guildford, UK; ³Royal London Hospital, London, UK.

ba0004p196

Benign osteopetrosis associated with homozygous mutation in CLCN7

Allgrove Jeremy Mathew Satheesh Buxton Chris C Williams Maggie

¹Barts Health NHS Trust, London, UK; ²Bristol Genetics Laboratory, Bristol, UK.

ba0004p197

Impaired mobility and pain significantly impact the quality of life of children with X-linked hypophosphatemia

Linglart Agnes Dvorak-Ewell Melita Marshall Ayla Martin Javier San Skrinar Alison

¹AP-HP, Bicêtre Hospital, Pediatric Endocrinology and French Reference Center for Rare Disorders of the Mineral Metabolism, Le Kremlin-Bicêtre, France; ²University Paris Sud, Le Kremlin-Bicêtre, France; ³Ultragenyx Pharmaceutical Inc., Novato, CA, USA.

ba0004p198

LRP5-associated high bone mass disorder: novel familial mutation in LRP5 and investigation of bone mineralization density distribution (BMDD)

Roetzer Katharina M Uyanik Goekhan Brehm Attila Zwerina Jochen Zandieh Shahin Czech Thomas Roschger Paul Klaushofer Klaus

¹Center for Medical Genetics, Hanusch Hospital, Vienna, Austria; ²Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, First Medical Department, Hanusch Hospital, Vienna, Austria; ³First Medical Department, Hanusch Hospital, Vienna, Austria; ⁴Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Vienna, Austria; ⁵Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.

ba0004p199

Relationship of lipid parameters and insulin resistance with bone health in South Korean adolescents

Kim Do-Hoon Park Sang-Woon Jung Dong-Wook Yoon Su-Jung Han Kyungdo Park Yong-Gyu Choi Jun-Seok Lee Jong-Eun Sang Jung-Eun Nam Ga-Eun Yoon Yeo-Joon

¹Department of Family Medicine, College of Medicine, Korea University, Seoul, Republic of Korea; ²Department of Biostatistics, Catholic University College of Medicine, Seoul, Republic of Korea.

ba0004p200

The results of pamidronate treatment independently and in combination with surgery in patients with osteogenesis imperfecta.

Zyma Andrii Guk Iurii Gayko Oksana Magomedov Oleksandr Kinchaya-Polishchuk Tamara Stewart David Cheverda Andriy Demyan Yuriy

¹Institute of Orthopedics and Traumatology, National Academy of Medical Sciences, Kiev, Ukraine; ²Children’s Bone and Spine Surgery, Las Vegas, NV, USA,.

ba0004p201

Bone Abstracts

7th International Conference on Children's Bone Health

Poster Presentations

BiosciAbstracts