Searchable abstracts of presentations at key conferences on calcified tissues
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43rd Annual European Calcified Tissue Society Congress

Rome, Italy
14 May 2016 - 17 May 2016

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Main Symposium

Insights from Outside: New Frontiers in Therapy

ba0005s2.2 | Insights from Outside: New Frontiers in Therapy | ECTS2016

Therapeutic potential of RNA interference

Aigner Achim

Since its discovery <20 years ago, RNA interference (RNAi) has proven to be a powerful tool for the downregulation of any target gene of choice. This also offers the use of RNAi-inducing small interfering RNAs (siRNAs) in a therapeutic setting, for the knockdown of pathologically overexpressed genes in various pathologies. Beyond siRNAs, this concept has been extended towards microRNAs (miRNAs) and their inhibitors.While the target cell provides the ...