Searchable abstracts of presentations at key conferences on calcified tissues
Bone Abstracts (2016) 5 P467 | DOI: 10.1530/boneabs.5.P467

ECTS2016 Poster Presentations Other diseases of bone and mineral metabolism (52 abstracts)

Disease activity in patients with rheumatoid arthritis according to vitamin D status

Nataliya Balatska 1 , Omelyan Synenky 2 & Vladyslav Povoroznyuk 1

1D.F. Chebotarev Institute of Gerontology NAMS of Ukraine, Kyiv, Ukraine; 2Lviv Regional Clinical Hospital, Lviv, Ukraine.

Introduction: Vitamin D deficiency is common in patients with rheumatoid arthritis and may be related to disease activity.

The aim of the study was to evaluate the association between 25(OH)D level and disease activity in patients with rheumatoid arthritis.

Materials and methods: The study included 61 patients with rheumatoid arthritis, 73.8% were women, 70.4 patients were younger 60 years old. Subjects suffering from liver and kidney insufficiency and those who had received vitamin D in the previous 3 months have been excluded. Disease activity was assessed by DAS-28 score, joint pain degree, morning stiffness time and laboratory measures including Hb and ESR.

The level of 25(OH)Dtotal was evaluated by electrochemiluminescence method (Elecsys 2010, Roche). Vitamin D deficiency was defined as a 25(OH)D below 20 ng/ml, and vitamin D insufficiency as 25(OH)D of 21–29 ng/ml.

Results: In patients with rheumatoid arthritis, the frequency of vitamin D insufficiency and deficiency was 32.8 and 55.7% accordingly. 14.7% subjects with rheumatoid arthritis had severe vitamin D deficiency. 25(OH)D was associated with morning stiffness (r=−0.35; P=0.04), ESR level (r=−0.36; P=0.05), DAS-28 (r=−0.24; P=0.05), Hb (r=0.27; P=0.01).

Summary: Physicians should consider 25(OH)D level in management of patients with rheumatoid arthritis.

Volume 5

43rd Annual European Calcified Tissue Society Congress

Rome, Italy
14 May 2016 - 17 May 2016

European Calcified Tissue Society 

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