Searchable abstracts of presentations at key conferences on calcified tissues
Previous issue | Volume 7 | ICCBH2019

9th International Conference on Children's Bone Health

Poster Presentations

(1)

Treatment of partial growth arrest using cylindrical costal osteochondral graft
Orthopaedic Surgery Osaka University Graduate School of Medicine, Suita, Japan.
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Response of bone to mechanical stimulation in the offspring of MAVIDOS study mothers in a single centre; the effect of antenatal vitamin D supplementation
1University of Sheffield, Sheffield, UK; 2Hull York Medical School, Hull University, Hull, UK; 3Department of Paediatric Endocrinology, University Hospital Southampton, Southampton, UK; 4MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; 5NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK; 6NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford; 7Sheffield Children’s NHS FT, Sheffield, UK.
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Pseudohypoparathyroidism type Ib initially masquerading as epileptic seizures due to Fahr's disease
1Department of Pediatrics, Klatovy Hospital, Klatovy, Czech Republic; 2Department of Pediatrics, Pardubice Hospital, Pardubice, Czech Republic; 3Department of Pediatrics, Faculty of Medicine and Faculty Hospital, Hradec Kralove, Czech Republic.
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Bone morphology patterns in children with osteogenesis imperfecta
1Hospital for Special Surgery, New York, USA; 2University of Michigan, Ann Arbor, USA.
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Do lifestyle factors play a role on bone health in boys diagnosed with Autism Spectrum Disorder? Preliminary data from the Promoting bone and gut health in our children (PROUD) study
1Institute for Physical Activity and Nutrtion, Deakin University, Geelong, Australia; 2Australian Institute for Musculoskeletal Sciences (AIMSS), Western Health, St Albans, Australia; 3Epi-Centre for Healthy Ageing, Deakin University, Geelong, Australia; 4Department of Foods and Nutrition, The University of Georgia, Athens, USA.
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Radiographic evidence of zoledronic acid given during pregnancy - a case report
1Sheffield Children’s Hospital, Sheffield, UK; 2The University of Sheffield, Sheffield, UK.
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Clinical implications of modeling the maturational spurt
1University of Missouri, Department of Orthopaedic Surgery, Columbia, SC, USA; 2University of Missouri, Department of Pathology and Anatomical Sciences, Columbia, SC, USA.
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Bone health in children with congenital heart disease
1University of Saskatchewan, Saskatoon, Canada; 2Unviersity of Regina, Regina, Canada.
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Higher neonatal bone mineral content and lower IL-6 levels in offspring of overweight/obese women following antenatal exercise: The IMPROVE randomized controlled trial (RCT)
1Department of Paediatrics, Faculty of Medicine, University of Colombo, Sri Lanka; 2Liggins Institute, University of Auckland, New Zealand; 3Department of Obstetrics and Gynacology, University of Auckland, New Zealand.
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Sex and maturation effects on trabecular and cortical microarchitecture in children and young adults
1Stanford School of Medicine Pediatrics, Palo Alto, CA, USA; 2UCSF, San Francisco, CA, USA.
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Bone mass and fracture prevalence in childhood brain cancer survivors (CBCS) 2 or 5 years after off therapy
1Department of Pediatrics, Giannina Gaslini Hospital, Italy, Genova, Italy; 2University of Genova, Genova, IT; 3Department of Neuro-Oncology, Giannina Gaslini Hospital, Italy, Genova, IT.
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Tibia microarchitecture in children with recent fractures
1MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; 2Paediatric Endocrinology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
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What happens to the skeleton at the time of diagnosis of paediatric cancer?
1Department of Bone and Mineral Metabolism, Institute of Child Health, Athens, Greece; 2Oncology Department, ‘P.&A. Kyriakou’ Children’s Hospital, Athens, Greece; 3Division of Endocrinology, Diabetes and Metabolism, 1st Department of Paediatrics, Medical School, National and Kapodistrian University of Athens, ‘Aghia Sophia’ Children’s Hospital, Athens, Greece; 42nd Department of Paediatrics, Medical School, National and Kapodistrian University of Athens, ‘P.&A. Kyriakou’ Children’s Hospital, Athens, Greece; 5Department of Endocrinology, Metabolism and Diabetes Mellitus, Nikaea-Piraeus General Hospital ‘Agios Panteleimon’, Greece.
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The role of the RACK1-c-Src axis in regulation of osteoclast function
Department of Life Science, Ewha Womans University, Seolu, South Korea.
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Short term mechanical stimulation using whole body vibration identifies differences in bone response between prepubertal boys with and without prior fracture
1University of Sheffield, Sheffield, UK; 2Sheffield Children’s NHS FT, Sheffield, UK; 3MRC Lifecourse Epidemiology Resource Unit, University of Southampton, Southampton, UK; 4University of Hull Medical School, Hull, UK.
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Parathyroid hormone is higher in infants with fracture as opposed to without fracture undergoing skeletal survey for suspected non-accidental injury, and is inversely associated with mean corpuscular haemoglobin content
1Sheffield Children’s NHS FT, Sheffield, UK; 2Chesterfield Royal Hospital, Chesterfield, UK; 3Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
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Response to mechanical stimulation of bone in children with osteogenesis imperfecta and the effect of bisphosphonate therapy
1University of Sheffield, Sheffield, UK; 2Sheffield Children’s NHS FT, Sheffield, UK; 3Hull York Medical School, Hull University, Hull, UK.
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Duchenne muscular dystrophy: preliminary results of the Risbo-DMD study
1Experimental Laboratory for Children’s Bone Metabolism Research, Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS, Milano, Italy; 2Unità Operativa Malattie Neuromuscolari, Fondazione Istituto Neurologico C. Besta IRCCS, Milano, Italy; 3Centro Clinico Nemo, Ospedale Niguarda, Milano, Italy; 4Istituto Medea IRCCS, La Nostra Famiglia, Bosisio Parini, Lecco, Italy; 5Dipartimento Neurologia Pediatrica, Policlinico Universitario Agostino Gemelli, Università Cattolica, Roma, Italy; 6UOC Neurologia e Malattie Neuromuscolari, Policlinico di Messina, Messina, Italy.
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Rib cage anomalies in a cohort of osteogenesis imperfecta patients
1Department of Traumatology and Orthopedics, University of Tartu, Tartu, Estonia; 2Clinic of Traumatology and Orthopedics, Tartu University Hospital, Department of Traumatology and Orthopedics, University of Tartu, Tartu, Estonia; 3Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam; 4Department of Pathophysiology, University of Tartu, Tartu, Estonia; 5Centre of Translational Medicine, University of Tartu, Tartu, Estonia; 6Perron Institute for Neurological and Translational Science, QEII Medical Centre, Nedlands, Australia.
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Bone mass, sclerostin and body composition in women with anorexia nervosa: a 3-year follow-up after weight gain therapy
1Department of Pediatrics, Institute for Clinical Sciences, The Queen Silvia Children’s Hospital, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; 2Department of Orthopaedics, Institute of Clinical Sciences, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; 3Anorexia-Bulimia Unit, The Queen Silvia Children’s Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden; 4Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Sweden; 5Department of Clinical Chemistry, Linköping University, Linköping, Sweden.
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Determinants of survival in osteogenesis imperfecta (OI) Type II
1Birmingham Children’s Hospital, Birmingham, UK; 2Johannes Kepler University, Linz, Austria.
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Successful use of oral acetazolamide in symptomatic subcutaneous calcifications in hyperphosphatemic tumoral calcinosis
1Birmingham Children’s Hospital, Birmingham, UK; 2Nottingham University Hospital NHS Trust, Nottingham, UK; 3John Radcliffe Hospital, UK; 4Johannes Keppler University, Linz, Austia.
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Unusual case of severe hypophosphataemic rickets and renal stones associated with valproate use
1Alder Hey Children’s Hospital, Liverpool, UK; 2Arrowe Park Hospital, Upton Wirral, UK.
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ALPL gene mutation in a family
Istituto Auxologico Italiano, IRCCS, Milano, Italy.
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Bone health outcomes in children with Duchenne Muscular Dystrophy
1The University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia; 2The Children’s Hospital at Westmead, Westmead, Australia.
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Increased prevalence of fractures in poorly chelated children with beta thalassemia
1Hirabai Cowasji Jehangir Medical Research Institute, Pune, India; 2Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital Manchester University NHS Foundation Trust, Oxford Road, Manchester, UK; 3Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Oxford Road, Manchester, UK; 4Department of Diabetes and Endocrinology, Birmingham Women’s and Children’s NHS Foundation Trust, Steelhouse Lane, Birmingham, UK.
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Bone health is compromised in adult patients with childhood-onset autoimmune-polyendocrinopathy-candiadis-ectodermal dystrophy (APECED)
1Helsinki University Hospital, Helsinki, Finland; 2University of Helsinki, Helsinki, Finland; 3Folkhälsan Research Center, Helsinki, Finland.
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Osteogenesis imperfecta type 15 with neurological phenotype associated with homozygous WNT1 mutation and uniparental isodisomy for chromosome 12
1Highly Specialised Osteogenesis Imperfecta Service, The Wolfson Neurodisability Service, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; 2Department of Paediatric Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; 3Clinical Genetics Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; 4Haemophilia Comprehensive Care Centre, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
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Vertebral fractures are more prevalent than long bone fractures in boys with glucocorticoid-treated Duchenne Muscular Dystrophy: Results of a prospective observational study
1Children’s Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada; 2Department of Pediatrics, University of Toronto, Toronto, Canada; 3Department of Health Research Methods, Evidence, and Impact McMaster University, Hamilton, Canada; 4Department of Pediatrics, University of Ottawa, Ottawa, Canada; 5Department of Medical Imaging, University of Ottawa, Ottawa, Canada; 6Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada; 7Department of Pediatrics, McGill University, Montreal, Canada; 8Department of Pediatrics, Queen’s University, Kingston, Canada; 9Department of Medicine, University of Alberta, Edmonton, Canada.
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Does improved genetic screening make it more difficult to diagnose Osteogenesis Imperfecta?
1Temple Street Children’s University Hospital, Dublin, Ireland; 2Discipline of Paediatrics, University of Dublin, Trinity College, Dublin, Ireland.
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Bone mineral density and vitamin D status in children with chronic neurological syndromes - clinical observations
1Department of Paediatric Propedeutics and Bone Metabolism Diseases, Medical University of Lodz, Lodz, Poland; 2Department of Paediatric Allergology, Gastroenterology and Nutrition, Medical University of Lodz, Lodz, Poland.
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Treatment with asfotase alfa for patients with infantile hypophosphatasia and screening plan of hypophosphatasia by low ALP level and dental findings in Korea
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
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Higher dose of burosumab is needed for treatment of children with severe forms of X-linked hypophosphatemia
1APHP, Reference Center for Rare Disorders of the Calcium and Phosphate Metabolism, Filiere OSCAR and Platform of Expertise for Rare Diseases Paris-Sud, Bicêtre Paris-Sud Hospital, Le Kremline Bicetre, France; 2Department of Clinical Medicine and Surgery, Division of Endocrinology, University of Naples Federico II, Naples, Italy; 3Paris Sud – Paris Saclay University, Faculté de Médecine, Le Kremlin- Bicêtre, France; 4APHP, Department of Endocrinology and Diabetology for children, Bicêtre Paris Sud Hospital, Le Kremlin- Bicêtre, France; 5APHP, Department of Endocrinology and Reproductive Diseases, Bicêtre Paris Sud Hospital, Le Kremlin- Bicêtre, France; 6APHP Department of Pediatric Radiology, Bicêtre Paris Sud Hospital, Le Kremlin- Bicêtre, France; 7APHP Department of ORL, Bicêtre Paris Sud Hospital, Le Kremlin- Bicêtre, France; 8Department of Odontology-Maladies Rares, Hospital Bretonneau, Paris, France; 9Université Paris Descartes, Paris, France; 10Department of Pediatric orthopaedic surgery, Necker - Sick Kids University Hospital, Paris, France; 11APHP, Department of Rheumatology Hospital Cochin, Paris, France; 12Pediatric Neurosurgery, Hospital Femme Mere Enfant, Hospices Civiles de Lyon and University Claude Bernard Lyon, Bron Cedex, France; 13Reference Center for Craniosynostosis, INSERM 1033, Lyon, France; 14APHP, Department of Molecular Genetics, Pharmacogenetics and Hormonology, Bice^tre Paris-Sud Hospital, Le Kremlin Bicêtre, France; 15Université Paris V, Faculté de Médecine, Paris, France; 16Hôpital Necker Enfants Malades APHP, INSERM U1151, Paris, France.
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Variable familial expression of spondylometaphyseal dysplasia with coxa vara and a novel FN1 mutation
1Department of Pediatrics, Innsbruck, Austria; 2Department of Orthopedics, Innsbruck, Austria; 3Department of Orthopedics, Innsbruck, Austria; 4Centre of Medical Genetics, Austria.
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Successful treatment with enzyme replacement therapy in a girl with severe infantile Hypophosphatasia
Eastern Switzerland Children’s Hospital, St. Gallen, Switzerland.
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Is oral health correlated with skeletal phenotype in primary metabolic bone diseases? A preliminary report of the Greek experience
1Department of Bone and Mineral Metabolism, Institute of Child Health, Athens, Greece; 2Department of Paediatric Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
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Unusual cause of abdominal pain in adolescent girl
1Third Faculty of Medicine, Charles University in Prague, Prague 10, Czech Republic; 2First Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic; 3First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
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Effective therapy with growth hormone of an adolescent patient with growth hormone deficiency and osteopetrosis: A case report
1Endocrinology, Growth and Development Department, ‘P. & A. Kyriakou’ Children’s Hospital, Athens, Greece; 21st Orthopaedic Surgery Department ‘P.&A. Kyriakou’ Children’s Hospital, Athens, Greece.
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The validity of serum alkaline phosphatase to identify nutritional rickets in Nigerian children on a calcium-deprived diet
1Mayo Clinic, Rochester, USA; 2Vitamin D Standardization Program LLC, Havre de Grace, USA; 3Loyola University Chicago, Chicago, USA; 4The Children’s Hospital at Westmead, Sydney, Australia; 5University of the Witwatersrand, Johannesburg, South Africa.
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Effective treatment of a patient with Hypophosphatemic Rickets leading to normal adult height
1Department of Endocrinology, Growth and Development, ‘P. & A. Kyriakou’ Children’s Hospital, Athens, Greece; 21st Orthopedic Department, ‘P.&A. Kyriakou’ Children’s Hospital, Greece.
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FGF23-expressing osteocytes are confined to bone packets that completed primary mineralization in patients with chronic kidney disease on dialysis (CKD5D)
1Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGK and AUVA Trauma Centre Meidling, 1st Medical Department, Hanusch Hospital, Vienna, Austria; 2Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, USA.
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Tissue non-specific alkaline phosphatase activity and mineralization capacity of bi-allelic mutations from severe perinatal and asymptomatic hypophosphatasia phenotypes: Results from an in-vitro mutagenesis model
1Department of Endocrinology and Diabetes, Birmingham Women’s and Children’s Hospital, Birmingham, UK; 2Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK; 3Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan; 4Department of Paediatrics and Adolescent Medicine, Johannes Kepler University, Linz, Austria.
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Bone geometry and microarchitecture deficits in children with Alagille syndrome
1The Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; 2St Christopher’s Hospital for Children and Department of Pediatrics at Drexel University School of Medicine, Philadelphia, PA, USA; 3Stanford School of Medicine, Palo Alto, CA, USA.
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Missense mutations in ENPP1 result in osteoporosis in patients and is recapitulated in the ENPP1 loss of function murine model
1Department of Pathology, Yale University Medical School, New Haven, CT, USA; 2Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 3Department of Orthopædics and Rehabilitation, Yale University School of Medicine, New Haven, CT, USA; 4Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.
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Tumor induced osteomalacia in a 12-year-old girl: Case report
1Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 2Department of Orthopedics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 3National Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, Thailand; 4Queen Sirikit National Institute of Child Health, Bangkok, Thailand.
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Bone densitometry and body composition in children with hypophosphatasia
1Department of Endocrinology and Diabetes, Birmingham Women’s and Children’s Hospital, Birmingham, UK; 2Department of Paediatrics and Adolescent Medicine, Johannes Kepler University, Linz, Austria.
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Bone health outcomes in children and adolescents with neuromuscular disease
1The Children’s Hospital at Westmead, Westmead, Australia; 2The University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia; 3Macquarie University, North Ryde, Australia.
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Clinical case of a child with a hereditary vitamin D dependent rickets type 1a, complicated by rachitic lung and oxygen dependence
1Morozov Children’s Municipal Clinical Hospital of the Moscow City Health Department, Moscow, Russian Federation; 2FSBI Research Center for Medical Genetic, Moscow, Russian Federation.
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Necessity of high dose and prolonged duration denosumab post stem cell transplant for TNFRSF11A osteoclast-poor autosomal recessive osteopetrosis
1Department of Paediatric Endocrinology, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust Bristol, Bristol, UK; 2Department of Blood and Marrow Transplantation, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust Bristol, Bristol, UK; 3Department of Pharmacy, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust Bristol, Bristol, UK; 4Department of Clinical Genetics, St Michaels Hospital, University Hospitals Bristol NHS Foundation Trust Bristol, Bristol, UK; 5Bristol Medical School: Translational Health Sciences, University of Bristol, Bristol, UK.
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Burosumab experience in UK X-linked hypophosphataemia children under five years old
1Alder Hey Children’s Hospital, Liverpool, UK; 2Bristol Royal Hospital for Children, Bristol, UK; 3Evelina Children’s Hospital, London, UK; 4Royal Manchester Children’s Hospital, Manchester, UK; 5Birmingham Children’s Hospital, Birmingham, UK; 6Nottingham Children’s Hospital, Nottingham, UK; 7Leeds Teaching Hospital, Leeds, UK; 8Royal Hospital for Sick Children, Edinburgh, UK; 9Southampton University Hospital, Southampton, UK; 10Sheffield Children’s Foundation Trust, Sheffield, UK; 11MAP BioPharma, Papworth Everard, Cambridge, UK; 12Kyowa Kirin, Galashiels, UK.
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Burosumab initiation in a UK X-linked hypophosphataemia cohort: real-world use resonates with research evidence
1Alder Hey Children’s Hospital, Liverpool, UK; 2Bristol Royal Hospital for Children, Bristol, UK; 3Evelina Children’s Hospital, London, UK; 4Royal Manchester Children’s Hospital, Manchester, UK; 5Birmingham Children’s Hospital, Birmingham, UK; 6Nottingham Children’s Hospital, Nottingham, UK; 7Leeds Teaching Hospital, Nottingham, UK; 8Royal Hospital for Sick Children, Edinburgh, UK; 9Southampton University Hospital, Southampton, UK; 10Sheffield Children’s Foundation Trust, Sheffield, UK; 11MAP BioPharma, Papworth Everard, Cambridge, UK; 12Kyowa Kirin, Galashiels, UK.
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Active vitamin D analogues and oral phosphate for the treatment of X-linked hypophosphataemia in paediatric patients: A systematic literature review and survey of expert opinion on current needs
1Hospital Universitario Materno-Infantil Vall d’Hebron, Universitat Autonoma de Barcelona, Barcelona, UK; 2Hospital Niño Jesús, Madrid, Spain; 3Medialis, Banbury, UK; 4Royal Manchester Children’s Hospital, Manchester, UK.
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Safety profile of asfotase alfa treatment of patients with hypophosphatasia: a pooled analysis
1Center for Metabolic Bone Disease and Molecular Research, Shriners Hospital for Children, Saint Louis, USA; 2Department of Oncology and Metabolism, University of Sheffield and Sheffield Children’s NHS FT, Sheffield, UK; 3Alexion Pharmaceuticals, Inc., Boston, USA; 4University Children’s Hospital, University of Würzburg, Würzburg, Germany; 5Department of Pediatrics and Adolescent Medicine, Johannes Kepler University Linz, Linz, Austria; 6University of Manitoba, Rady Faculty of Health Sciences, Max Rady College of Medicine, and Children’s Hospital Research Institute of Manitoba, Winnipeg, Canada; 7Covance, Inc., Princeton, USA; 8Department of Pediatrics, Duke University Medical Center, Durham, USA.
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Long-term efficacy profile of asfotase alfa in the treatment of patients with hypophosphatasia: a pooled analysis
1University of Sheffield, Sheffield, UK; 2Department of Pediatrics and Adolescent Medicine, Johannes Kepler University Linz, Linz, Austria; 3University of Manitoba, Rady Faculty of Health Sciences, Max Rady College of Medicine, and Children’s Hospital Research Institute of Manitoba, Winnipeg, Canada; 4Alexion Pharmaceuticals, Inc., Boston, USA; 5Covance, Inc., Princeton, USA; 6Center for Metabolic Bone Disease and Molecular Research, Shriners Hospital for Children-St.Louis, Saint Louis, USA.
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Novel imaging approaches to the quantification of musculoskeletal alterations in X-linked hypophosphatemic rickets (XLH)
1University Department of Pediatric and Adolescent Medicine, Division of Pediatric Pulmonology, Allergology and Endocrinology, Medical University of Vienna, Vienna, Austria; 2University Department of Biomedical Imaging and Image-guided Therapy, Division of General and Paediatric Radiology, Vienna, Austria; 3University Department of Surgery, Division of Pediatric Surgery, Medical University of Vienna, Vienna, Austria; 4University Department of Biomedical Imaging and Image-guided Therapy, The High Field MR Centre, Vienna, Austria; 5University Department of Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria; 6Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Berlin, Germany; 7Institute of Pathophysiology and Allergy Research, Center of Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria.
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Characterization of pain in patients with fibrous dysplasia
1Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, USA; 2Botnar Research Centre, Nuffield Department of Orthopaedics, NDORMS, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
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Could digital X-ray radiogrammetry be an alternative for dual energy X-ray absorptiometry
1Radboudumc Amalia Children’s Hospital, department of General Paediatrics, Nijmegen, Netherlands; 2Radboudumc, Department of Radiology and Nuclear Medicine, Nijmegen, Netherlands.
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Neonatal calcinosis cutis due to a mutation in the GNAS gene
1Pediatric Endocrinology and Diabetes Unit, The Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; 2The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; 3The Genomic Unit, Sheba Cancer Research Center, Tel Hashomer, Ramat-Gan, Israel; 4Pediatric Dermatology service, The Department of Dermatology, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel.
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Disease-specific pathological traits of youth at risk of secondary osteoporosis as determined through peripheral Quantitative Computed Tomography
1The University of Notre Dame Australia/Institute for Health Research, Fremantle, Australia; 2Edith Cowan University, Joondalup, Australia; 3University of Jyvaskyla, Jyvaskyla, Finland; 4Perth Children’s Hospital, Nedlands, Australia; 5Griffith University, Brisbane, Australia.
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Assessment of bone density by DXA in poorly controlled children with β-Thalassemia: Correction for hepatic iron - overloadby manual analysis
1Hirabai Cowasji Jehangir Medical Research Institute, Pune, India; 2Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital Manchester University NHS Foundation Trust, Manchester, UK; 3Department of Diabetes and Endocrinology, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK.
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Diagnostic performance of morphometric vertebral fracture analysis (MXA) in children using a 33-point software programme
1Academic Unit of Child Health, University of Sheffield, Sheffield, UK; 2Department of Radiological Sciences, College of Applied Medical Sciences, Najran University, Najran, Kingdom of Saudi Arabia; 3Department of Endocrinology and Diabetes, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK; 4Imaging Sciences Research Group, University of Manchester, Manchester, UK; 5Radiology Department, Sheffield Children’s NHS Foundation Trust, Sheffield, UK.
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Use of DXA and pQCT measurements to screen for fracture risk in 3 to 18 year old poorly chelated thalassaemic children
1Hirabai Cowasji Jehangir Medical Research Institute, Pune, India; 2Yashoda Hematology Clinic, Pune, Pune; 3Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital Manchester University NHS Foundation Trust, Mancheste, UK; 4Department of Diabetes and Endocrinology, Birmingham Women’s and Children’s NHS Foundation Trust, UK.
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Osteogenesis imperfecta due to FKBP10 mutation- shift from high to low bone turnover
1Department of Pediatrics, Division of Endocrinology, Hospital for Sick Children, University of Toronto, Toronto, Canada; 2Department of Pediatric Surgery, Division of Orthopaedics, Hospital for Sick Children, University of Toronto, Toronto, Canada; 3Joint Department of Medical Imaging, Toronto General Research Institute, University Health Network; Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.
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Bone health index by hand X-ray compared with bone mineral density by dual-energy X-ray absorptiometry in children with Duchenne muscular dystrophy
1Department of Radiology, Nationwide Children’s Hospital, Columbus, USA; 2Department of Endocrinology, Nationwide Children’s Hospital, Columbus, USA.
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A little girl with bowing of legs, a short mother and a waddling sister: Metaphyseal Chondrodysplasia, Schmid type
1Faculty of Medicine, University of Colombo, Colombo, Sri Lanka; 2Lady Ridgeway Hospital for Children, Colombo, Sri Lanka.
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Assessing the ability of vibration analysis to differentiate wrist and ankle fractures from sprains in children
1University of Sheffield, Sheffield, UK; 2Sheffield Hallam University, Sheffield, UK.
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Characteristics of ultradistal radius bone density during childhood: results from the Bone Mineral Density in Childhood Study
1The Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Creighton University, Omaha, Nebraska, USA; 3Children’s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA; 4Columbia University, New York, New York, USA; 5University of Hawaii, Honolulu, Hawaii, USA; 6National Institutes of Health, National Institute of Child Health and Human Development, Bethesda, Maryland, USA; 7Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA.
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Detection of intact FGF23 using a novel well-characterized ELISA
1The Antibody Lab GmbH, Vienna, Austria; 2Biomedica Medizinprodukte GmbH, Vienna, Austria.
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Radiofrequency echographic multispectrometry (REMS): a new approach for osteoporosis diagnosis in adolescents
1Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy; 2National Council of Research, Institute of Clinical Physiology, Lecce, Italy.
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Association of serum alkaline phosphatase with radiological rickets severity in children with X-linked hypophosphataemia on conventional therapy
1Department of Diabetes and Endocrinology, Birmingham Women’s and Children’s Hospital, Birmingham, UK; 2Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK; 3Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK; 4Department of Paediatric Endocrinology and Diabetes, Nottingham University Hospital, Nottingham, UK; 5Department of Paediatric and Adolescent Medicine, Johannes Kepler University, Linz, Austria; 6Department of Radiology, Evelina London Children’s Hospital, London, UK.
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The effect of vitamin D on bone health assessed by radiogrammetry: a double-blind placebo-controlled vitamin D supplementation trial in infants
1Department of Diabetes and Endocrinology, Birmingham Women’s and Children’s Hospital, Birmingham, UK; 2Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK; 3Institute of Applied Health Research, University of Birmingham, Birmingham, UK; 4College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; 5Department of Paediatric Endocrinology, Manchester Children’s Hospital, Manchester, UK; 6Department of Paediatrics and Adolescent Medicine, Johannes Kepler University, Linz, Austria.
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Pre and post-natal achondroplasia, retrospective series of 64 consecutives cases with analyze of the diagnostic methods and timing issues
1Department of Medical Genetics, Centre of Reference for Skeletal Dysplasia, Necker-Enfants Malades Hospital (AP-HP), Institut IMAGINE, University Paris Descartes, Paris, France; 2Department of Molecular Genetics, Necker-Enfants Malades Hospital (AP-HP), University Paris Descartes, Paris, France; 3Department of Radiology, Necker-Enfants Malades Hospital (AP-HP), University Paris Descartes, Paris, France; 4Department of Foetopathology, Necker-Enfants Malades Hospital (AP-HP), University Paris Descartes, Paris, France; 5Department of Obstetrics, Necker-Enfants Malades Hospital (AP-HP), University Paris Descartes, Paris, France.
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High-resolution MRI assessment of the muscle-fat-bone unit in young adults with childhood onset Crohn's disease
1Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, UK; 2Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK; 3MRI Physics, Department of Physics & Bioengineering, NHS Greater Glasgow & Clyde, Glasgow, UK; 4Department of Gastroenterology, NHS Greater Glasgow & Clyde, Glasgow, UK; 5Department of Paediatric Gastroenterology, The Royal Hospital for Children, Glasgow, UK.
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Vitamin D levels among Lebnaese children: Do we need to alter normal level?
1Beirut Arab University, Saida, Lebanon; 2Ain WaZein Medical Village, Ain WaZein, Lebanon.
ba0007p101
Vitamin D deficiency nutritional rickets presenting to secondary care in children (<16 Years) - A United Kingdom surveillance study
1Birmingham Children’s Hospital, Birmingham, UK; 2Royal Manchester Children’s Hospital, Manchester, UK; 3Royal Free London NHS Foundation Trust, London, UK; 4Royal College of Paediatrics & Child Health, London, UK; 5Great Ormond Street Hospital, London, UK; 6Temple Street Children’s Hospital, Dublin, Ireland; 7Royal Hospital for Sick Children, Glasgow, UK; 8Northwick Park Hospital, London, UK.
ba0007p104
Respiratory health impacts quality of life for adults with OI
1Hospital for Special Surgery, New York, USA; 2Alphanet; National Jewish Health, Littleton, USA.
ba0007p105
Scoliosis and cardiopulmonary outcomes in adults with osteogenesis imperfecta: a pilot study
1Hospital for Special Surgery, New York, USA; 2Alphanet; National Jewish Health, Littleton, USA.
ba0007p106
Sex differences in the longitudinal associations between body composition and bone stiffness index in European children and adolescents
1Leibniz Institute for Prevention Research and Epidemiology–BIPS, Bremen, Germany; 2Faculty of Mathematics and Computer Science, University of Bremen, Bremen, Germany; 3Institute of Food Sciences, National Research Council, Avellino, Italy; 4Department of Chronic Diseases, National Institute for Health Development, Tallinn, Estonia; 5Research and Education Institute of Child Health, Strovolos, Cyprus; 6National Institute of Health Promotion, University of PeÂcs, PeÂcs, Hungary; 7Section for Epidemiology and Social Medicine (EPSO), Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 8Department of Public Health, Ghent University, Ghent, Belgium; 9GENUD (Growth, Exercise, Nutrition and Development) Research Group, Instituto Agroalimentario de Aragón (IA2), Instituto de Investigación Sanitaria Aragón (IIS Aragón), Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBERObn), University of Zaragoza, Zaragoza, Spain; 10Centre for Exercise, Nutrition & Health Sciences, University of Bristol, Bristol, UK.
ba0007p107
Fracture prevalence in children 0-19 years-old in Mexico: A 10-year cross-sectional analysis
1Hospital Infantil de Mexico Federico Gomez, Mexico; 2Instituto Mexicano del Seguro Social, Mexico; 3Universidad Nacional Autónoma de México, Mexico; 4Instituto Nacional de Salud Pública, Mexico.
ba0007p109
Cost-effectiveness of a Vitamin D supplementation programme in pregnant women and children to prevent rickets in the UK
1Royal Manchester University Hospital, Manchester, UK; 2North Manchester General Hospital, Manchester, UK; 3Dolon Ltd, London, UK.
ba0007p110
Vitamin D dependent rickets type 1 caused by CYP27B1 mutation
Chonnam Natl. Univ. Hospital, Gwangju, South Korea.
ba0007p111
Case report: investigation of an osteolytic lesion leading to the diagnosis of congenital generalized lipodystrophy due to a novel AGPAT2 mutation
1Pediatric Endocrinology and Diabetes Unit, Dana-Dwek Children’s Hospital, Tel Aviv, Israel; 2Pediatric Orthopedic Department, Dana-Dwek Children’s Hospital, Tel Aviv, Israel; 3Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
ba0007p112
Next-generation sequence and biomarker levels in the patients with early-onset chronic non-bacterial osteomyelitis from North Caucasian region of Russia
1Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Saint-Petersburg, Russian Federation; 2N.N. Petrov Institute of Oncology, Saint-Petersburg, Russia; 3Science research Institute of Phthisiopulmonology, Saint-Petersburg, Russia; 4Republican Children’s Clinical Hospital, Makhachkala, Russia; 5Dagestan State Medical Academy, Makhachkala, Russia; 6Children’s Rehabilitation Center Detskye Duny, Saint-Petersburg, Russia; 7The University of Tokyo, Tokyo, Japan.
ba0007p113
Hypophosphatasia in Japan: ALPL mutation analysis in 98 patients
1Department of Bone and Mineral Research, Osaka Women’s and Children’s Hospital, Izumi, Japan; 2Department of Pediatrics, Osaka University Graduate School of Medicine, Izumi, Japan.
ba0007p114
Mabry Syndrome is a cause of hyperphosphatasia and mental retardation
1Leeds Teaching Hospitals NHS Trust, Leeds, UK; 2Department of Paediatric Endocrinology, Royal Manchester Childrens’ Hospital, Manchester, UK.
ba0007p115
Molecular genetic diagnosis and genotype-phenotype correlations in children and adolescents with recurrent fractures
The University of Sydney Children’s Hospital Westmead Clinical School, Westmead, Australia.
ba0007p116
Use of Lego® to explain genetic variations in type 1 collagen - a pilot study
1Great Ormond Street Hospital for Children, Consultant, London, UK; 2Great Ormond Street Hospital for Children, Clinical Nurse Specialist, London, UK; 3Great Ormond Street Hospital for Children, Physiotherapist, London, UK; 4Great Ormond Street Hospital for Children, Occupational Therapist, London, UK; 5Great Ormond Street Hospital for Children, Clinical Psychologist, London, UK.
ba0007p117
Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with bone disease severity in Rett syndrome
1Department of Medicine, Surgery and Neuroscience, of Siena, Siena, Italy; 2Paediatrics Neuropsychiatry Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
ba0007p118
A novel mutation in FAM111A gene in child with Kenny-Caffey syndrome type 2 presenting with short statue, medullary stenosis and hypoparathyroidism
1Endocrine Unit/Department of Pediatrics/King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Excellent Centre of Genetic/Department of Pediatrics/King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
ba0007p119
Congenital hyperinsulinism of infancy in a child with autosomal dominant hypocalcaemia type 1 due to an activating calcium sensing receptor mutation
1Royal London Hospital. Barts Health NHS Trust, London, UK; 2Great Ormond Street Hospital, London, UK; 3Centre for Endocrinology, Queen Mary University, London, UK.
ba0007p122
Odontochondrodysplasia in association with a TRIP11 mutation
1Department of Paediatric Endocrinology, Temple Street Children’s University Hospital, Dublin, Ireland; 2Discipline of Paediatrics, University of Dublin, Trinity College, Dublin, Ireland.
ba0007p123
SCN8a mutations and osteoporosis. Is osteocyte dysfunction the cause or the consequence?
1Department of Paediatric Endocrinology, Temple Street Children’s University Hospital, Dublin, Ireland; 2Discipline of Paediatrics, University of Dublin, Trinity College, Dublin, Ireland; 3Department of Paediatric Neurology, Temple Street Children’s University Hospital, Dublin, Ireland.
ba0007p125
Anemia - novel clinically significant finding during intravenous pamidronate therapy of children diagnosed with osteogenesis imperfecta
1Medical University of Lodz, Department of Pediatric Propedeutics and Bone Metabolic Diseases, Lodz, Poland; 2Department of Biostatistics and Translational Medicine, Medical University of Lodz, Lodz, Poland; 3Students’ Scientific Association in the Department of Pediatric Propedeutics and Bone Metabolic Diseases, Lodz, Poland.
ba0007p126
Burosumab therapy in pediatric patients with X-linked hypophosphatemia improves body composition
1Pediatric Endocrinology and Diabetes Unit, Dana-Dwek Children’s Hospital, Tel Aviv, Israel; 2Pediatric Nephrology Unit, Dana-Dwek Children’s Hospital, Tel Aviv, Israel; 3Pediatric Orthopedic Department, Dana-Dwek Children’s Hospital, Tel Aviv, Israel; 4Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
ba0007p127
Growth hormone effect on bone mineral density in a girl with osteogenesis imperfecta - a case presentation
1Department of Endocrinology-Growth and Development, ‘P&A Kyriakou’ Children’s Hospital, Athens, Greece; 2Department of Bone and Mineral Metabolism, Institute of Child Health, Athens, Greece; 3Division of Biochemistry-Hormonology, ‘P&A Kyriakou’ Children’s Hospital, Athens, Greece.
ba0007p128
Off label uses of pamidronate in rare pediatric bone diseases (Jansen's Metaphyseal Chondrodysplasia and Generalized Arterial Calcification of Infancy): A four year perspective
1Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, USA; 2Feinberg School of Medicine, Chicago, USA; 3MassGeneral Hospital for Children, Boston, USA.
ba0007p130
Losartan reduces circulating TGFb and CTX and increases vertebral bone mass in the OIM mouse
1University of Sheffield, Sheffield, UK; 2Sheffield Children’s NHS FT, Sheffield, UK; 3Reconstructive Sciences, University of Connecticut Health Centre, Farmington, CT, USA.
ba0007p133
First report of skin reaction with Zoledronic Acid
CHU Sainte-Justine – University of Montreal, Montreal, Canada.
ba0007p134
Oral ibandronate therapy in patients with osteogenesis imperfecta
1Klatovy Hospital, Klatovy, Czech Republic; 2Department of Pediatrics, Faculty of Medicine and Faculty Hospital, Hradec Kralove, Czech Republic; 3Department of Pediatrics, Pardubice Hospital, Pardubice, Czech Republic.
ba0007p135
Reversion to pamidronate after switch to zoledronic acid in children with bone disease
1Sheffield Children’s Hospital, Sheffield, UK; 2The University of Sheffield, Sheffield, UK.
ba0007p137
Growth hormone therapy in a child with severe short stature due to Miller-McKusick-Malvaux (3M) syndrome-2
1Faculty of Medicine, University of Colombo, Colombo, Sri Lanka; 2Faculty of Medicine, University of Kelaniya, Sri Lanka; 3William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University, London, UK.
ba0007p139
Safety and effectiveness of stoss therapy in children
1The Children’s Hospital at Westmead, Westmead, Australia; 2The University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia; 3Macquarie University, North Ryde, Australia; 4BIOCeuticals, Alexandria, Australia.
ba0007p140
Hypercalcaemia and osteonecrosis of the jaw in association with denosumab use in the paediatric population
1The Children’s Hospital at Westmead, Westmead, Australia; 2Macquarie University, North Ryde, Australia; 3The University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia; 4Sainte Justine University Hospital Centre, Montreal, Canada; 5University of Montreal, Montreal, Canada.
ba0007p141
Protocol: a randomized trial of zoledronate in children with cerebral palsy
1Child and Youth, Randers Regional Hospital, Randers, Denmark; 2Danish Orthopaedic Research, dpor.dk, Aarhus, Denmark; 3Osteoporosis Clinic, Aarhus University Hospital, Aarhus, Denmark; 4Child and Youth, Aarhus University Hospital, Aarhus, Denmark; 5Child and Youth, Regional Hospital West, Herning, Denmark; 6Department of Pediatrics, Aalborg University Hospital, Aalborg, Denmark.
ba0007p142
Intermittent bi-daily sub-cutaneous teriparatide infusion in children with hypoparathyroidism: a single-centre experience
1Reference Center for Rare Diseases of Calcium and Phosphate, Lyon, France; 2Service de Néphrologie et Rhumatologie Pédiatrique-Hôpital Femme Mère Enfant, Bron, France; 3LYOS INSERM U1033 Pathophysiology, Diagnosis and treatments of Bone Diseases, Lyon, France.
ba0007p143
A multi-criteria decision analysis of the value of burosumab for the treatment of paediatric patients with X-linked hypophosphatemia in Portugal
1Associação Nacional de Displasias Ósseas, Évora, Portugal; 2Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal; 3Centro Hospitalar São João, Porto, Portugal; 4Centro Hospitalar Universitário Coimbra, Coimbra, Portugal; 5Kyowa-Kirin International, Marlow, UK; 6Exigo Consultores, Lisbon, Portugal.
ba0007p144
Does prior bisphosphonate therapy in children and adolescents with cerebral palsy alter surgical outcomes?
1Sainte Justine University Hospital Centre, Montreal, Canada; 2University of Montreal, Montreal, Canada; 3The University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia; 4The Children’s Hospital at Westmead, Westmead, Australia; 5Macquarie University, North Ryde, Australia; 6Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
ba0007p146
Changes in DXA Z-scores during bisphosphonate (BP) therapy in patients with osteogenesis imperfecta (OI) at a tertiary care hospital in South Africa
C.H Baragwanath Academic Hospital, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand., Johannesburg, South Africa.
ba0007p147
Management of foramen magnum stenosis in patients with achondroplasia: relative merit of clinical and radiological indications for foramen magnum decompression
1Department of Paediatric Neurosurgery, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK; 2Department of Paediatric Orthopaedics, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK; 3Department of Clinical Genetics, St Michaels Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, UK; 4Department of Paediatric Endocrinology, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
ba0007p148
Bone mineral changes in 43 children with osteogenesis imperfecta treated by pamidronate
1Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Saint-Petersburg, Russian Federation; 2City Children’s Hospital #1, Saint-Petersburg, Russian Federation; 3The Turner Scientific Research Institute For Children’s Orthopedics, Saint-Petersburg, Russian Federation.
ba0007p149
The safety and efficacy of denosumab versus zoledronic acid in the treatment of pediatric osteoporosis: a randomized controlled pilot trial
1Shriners Hospital for Children - Canada, McGill University, Montreal, Canada; 2Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada; 3Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Canada; 4Department of Pediatrics, University of Ottawa, Ottawa, Canada; 5Department of Medical Imaging, Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada; 6Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada; 7Department of Pediatrics, Queen’s University, Kingston, Canada; 8Department of Radiology and Diagnostic Imaging and Department of Medicine, University of Alberta, Edmonton, Canada.
ba0007p151
An evaluation of the rebound phenomenon during denosumab therapy in children with low turnover osteoporosis
1Shriners Hospital for Children - Canada, McGill University, Montreal, Canada; 2Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada; 3Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Canada; 4Department of Pediatrics, University of Ottawa, Ottawa, Canada; 5Department of Medical Imaging, Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada; 6Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada; 7Department of Pediatrics, Queen’s University, Kingston, Canada; 8Department of Radiology and Diagnostic Imaging and Department of Medicine, University of Alberta, Edmonton, Canada.
ba0007p152
Self-reported sedentary time is negatively associated with microarchitecture of the tibia
1MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; 2Paediatric Endocrinology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
ba0007p154
Gender specific paediatric reference data for muscle function parameters assessed using jumping mechanography
1Hirabai Cowasji Jehangir Medical Research Institute, Pune, India; 2Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester University, Manchester, UK; 3Novotec Medical GmbH, Pforzheim, Germany.
ba0007p155
Patients with nephropatic cystinosis display lower cortical thickness and grip strength
1Interdisciplinary Cystinosis Clinics, iSPZ, Dr. von Haunersche Kinderklinik, LMU Munich, Munich, Germany; 2Cystinose Stiftung, Munich, Germany.
ba0007p156
Endocrinological complications in Czech paediatric patients with Duchenne muscular dystrophy
1Department of Paediatric Neurology, 2nd Faculty of Medicine of Charles University in Prague and University Hospital Motol, Prague, Czech Republic; 2Department of Pediatrics, 2nd Faculty of Medicine of Charles University in Prague and University Hospital Motol, Prague, Czech Republic.
ba0007p161
Bone monitoring and morbidity in adults with duchenne muscular dystrophy: Challenges in implementation of standards of care
1Developmental Endocrinology Research Group, Royal Hospital for Children, Glasgow, UK; 2Scottish Muscle Network, Queen Elizabeth University Hospital, Glasgow, UK; 3Department of Respiratory, Queen Elizabeth University Hospital, Glasgow, UK; 4Department of Diabetes and Endocrinology, Queen Elizabeth University Hospital, Glasgow, UK; 5Department of Neurology, Queen Elizabeth University Hospital, Glasgow, UK.
ba0007p162
Prenatal oligohydramnios is associated with hip shape in adolescent males
1Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; 2MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; 3Population Health Science, Bristol Medical School, Bristol University, Bristol, UK; 4Bristol NIHR Biomedical Research Centre, Bristol, UK; 5Aberdeen Centre for Arthritis and Musculoskeletal Health, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK; 6Musculoskeletal Science and Sports Medicine Research Centre, Manchester Metropolitan University, Manchester, UK.
ba0007p163
Musculoskeletal deficits persist up to two years despite anti-TNF-alpha antibody therapy in children with Crohn's disease: Results of a prospective, observational inception cohort study
1Children’s Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada; 2Department of Health Research Methods, Evidence, and Impact McMaster University, Hamilton, Canada; 3Department of Pediatrics, CHEO IBD Centre, University of Ottawa, Ottawa, Canada; 4Department of Pediatrics, University of Ottawa, Ottawa, Canada; 5Department of Pediatrics, McGill University, Montreal, Canada; 6Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA; 7Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA; 8Department of Medical Imaging, University of Ottawa, Ottawa, Canada; 9Department of Radiology, University of British Columbia, Vancouver, Canada; 10Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada; 11Department of Medicine, University of Alberta, Edmonton, Canada.
ba0007p164
Fibroblast growth factor-21 (FGF-21) - marker of mineral bone disorder
1Nationale Institute of Children’s Diseases of Faculty of Medicine, Comenius University, Bratislava, Slovakia; 2Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
ba0007p165
Children's multivitamins do not contain sufficient vitamin D
1MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; 2Paediatric Endocrinology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
ba0007p167
Rescue diet restores bone matrix mineralization in mice with a non-functioning vitamin D receptor
1Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 1st Medical Department, Hanusch Hospital, Wien, Austria; 2Orthopaedic Hospital Vienna Speising, Wien, Austria; 3Department of Biomedical Sciences, University of Veterinary Medicine, Wien, Austria.
ba0007p169
Serum 25-hydroxyvitamin D requirements to prevent rickets in Nigerian children on a calcium-deprived diet
1Mayo Clinic, Rochester, USA; 2Vitamin D Standardization Program LLC, Havre de Grace, USA; 3Loyola University Chicago, Chicago, USA; 4The Children’s Hospital at Westmead, Sydney, Australia; 5University of the Witwatersrand, Johannesburg, South Africa.
ba0007p170
Seasonal variations in vitamin D status in children with haematological malignancies in Sweden
1Department of Women’s and Children’s Health, University Children’s Hospital, Uppsala, Sweden; 2Department of Molecular Medicine and Surgery, Karolinska Institute, and Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden; 3Department of Clinical Chemistry and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
ba0007p171
Cow's milk allergic infants on amino acid-based medical nutrition formula maintain adequate serum concentrations of phosphorus, calcium and magnesium despite the use of acid-suppressive medication
1Children’s Investigational Research Program, LLC (ChiRP), Bentonville, USA; 2Danone Nutricia Research, Nutricia Advanced Medical Nutrition, Utrecht, The Netherlands; 3Maastricht University, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, The Netherlands.
ba0007p172
Supplementation of children with type 1 diabetes with milk or pharmacological calcium for improving bone health - a randomized controlled trial
1Hirabai Cowasji Jehangir Medical Research Institute, Pune, India; 2Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital Manchester University NHS Foundation Trust, Manchester, UK.
ba0007p174
Dietary behaviours and compromised nutritional intakes in children with Osteogenesis Imperfecta
1Department of Paediatric Therapies, Bristol Royal Hospital for Children, University Hospital Bristol NHS Foundation Trust, Bristol, UK; 2Highly Specialised Complex Childhood Osteogenesis Imperfecta Service, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK; 3Bristol Medical School, Department of Translational Health Sciences, University of Bristol, Bristol, UK; 4Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK; 5Department of Paediatric Endocrinology and Diabetes, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
ba0007p175
Prevalence of vitamin D deficiency in newly diagnosed children with cancer
Nemours/A.I. duPont Hospital for Children, Wilmington, USA.
ba0007p176
Feasibility of a 13-week targeted exercise intervention on tibial bone mineral density in adolescents with Developmental Coordination Disorder
1The University of Notre Dame Australia/Institute for Health Research, Fremantle, Australia; 2Perth Children’s Hospital, Nedlands, Australia; 3Edith Cowan University, Joondalup, Australia; 4University of Jyvaskyla, Jyvaskyla, Finland.
ba0007p177
Clinical and radiological characteristics of children's forearm deformations with hereditary multiple exostosis (Clinical observation)
The Turner Scientific and Research Institute for Children’s Orthopedics, Saint-petersburg, Russian Federation.
ba0007p179
Walking quality of children with healed Perthes disease
1The Children’s Hospital at Westmead, Westmead, Australia; 2The University of Sydney Children’s Hospital at Westmead Clinical School, Sydney, Australia; 3Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 4Macquarie University, North Ryde, Australia.
ba0007p181
Material based on bioactive glass to replace bone defects in children after removal of tumors
1Institute of Traumatology and Orthopedics of NAMS of Ukraine, Kiev, Ukraine; 2Bogomolets National Medical University, Ministry of Ukraine, Kiev, Ukraine.
ba0007p184
High impact exercise to improve musculoskeletal outcomes in Crohn's disease: a feasibility questionnaire
1Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, UK; 2Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK; 3Department of Gastroenterology, NHS Greater Glasgow & Clyde, Glasgow, UK; 4Department of Paediatric Gastroenterology, The Royal Hospital for Children, Glasgow, UK.
ba0007p185
Severe osteoporosis with life threatening vertebral fractures in a 15-years-old boy with juvenile idiopathic arthritis: a successful spinal cord decompression and posterior spinal fusion Th2-Th12
1Department of Pediatric Rheumatology, Immunology, and Metabolic Bone Diseases, Medical University of Bialystok, Bialystok, Poland; 2Department of Pediatric Orthopedics and Traumatology, Medical University of Bialystok, Bialystok, Poland.
ba0007p186
Increased prevalence of overweight and obesity and its clinical predictors in children affected by X-linked hypophosphatemia
1APHP, Reference Center for Rare Disorders of the Calcium and Phosphate Metabolism, Filiere OSCAR and Platform of expertise for rare diseases Paris-Sud, Bicêtre Paris-Sud Hospital, Le Kremlin-Bicêtre, France; 2Department of Clinical Medicine and Surgery, Division of Endocrinology, University of Naples Federico II, Naples, Italy; 3APHP, Department of Endocrinology and Diabetology for children, Bicêtre Paris Sud Hospital, Le Kremlin-Bicêtre, France; 4IRCCS SDN, Naples, Italy; 5APHP, Department of Endocrinology and Reproductive Diseases, Bicêtre Paris Sud Hospital, Le Kremlin-Bicêtre, France; 6APHP, Department of Molecular Genetics, Pharmacogenetics and Hormonology, Bicêtre Paris-Sud Hospital, Le Kremlin-Bicêtre, France; 7Université Paris V, Faculté de Médecine, Paris, France; 8Hôpital Necker Enfants Malades APHP, INSERM U1151, Paris, France; 9APHP, Department of Adolescent Medicine, Bicêtre Paris Sud Hospital, Le Kremlin-Bicêtre, France; 10Paris Sud – Paris Saclay University, Faculté de Médecine, Le Kremlin-Bicêtre, France.
ba0007p187
Cleidocranial dysplasia: a patient with severe dental phenotype
1Department of Bone and Mineral Metabolism, Institute of Child Health, Athens, Greece; 2Department of Paediatric Dentistry, Dental School, National and Kapodistrian University of Athens, Athens, Greece; 3Department of Genetics, Institute of Child Health, Athens, Greece.
ba0007p189
Cone-shaped epiphyses involving the knees: report of a case and differential diagnosis
1Department of Bone and Mineral Metabolis, Institute of Child Health, Athens, Greece; 21st Department of Paediatrics, Medical School, National and Kapodistrian University of Athens, ‘Agia Sophia’ Children’s Hospital, Athens, Greece; 3Department of Radiology, ‘Agia Sophia’ Children’s Hospital, Athens, Greece; 4Department of Paediatric Orthopaedics, ‘Agia Sophia’ Children’s Hospital, Athens, Greece.
ba0007p190
Double trouble: A case of trisomy 21 and achondroplasia
Royal Hospital for Children, Glasgow, UK.
ba0007p193
Skeletal dysplasia in Saul Wilson syndrome
Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
ba0007p194
Growth velocity measured by biomarker, COLX, in Achondroplasia
Center for Rare Diseases, Rigshospitalet, Copenhagen, Denmark.
ba0007p195
Sleep related problems in children with osteogenesis imperfecta
Sheffield Children’s NHS Foundation Trust, Sheffield, UK.
ba0007p196
Diversity of outcomes in randomised trials of interventions for children with osteogenesis imperfecta
1The Children’s Hospital at Westmead, Westmead, Australia; 2The University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia; 3Macquarie University, North Ryde, Australia.
ba0007p199
Whole body vibration training for children and adolescents with congenital myopathy
1Macquarie University, North Ryde, Australia; 2The Children’s Hospital at Westmead, Westmead, Australia; 3The University of Sydney Children’s Hospital at Westmead Clinical School, Sydney, Australia; 4Murdoch Children’s Research Institute, Melbourne, Australia.
ba0007p200
Juvenile dermatomyositis (JDM) and hypoparathyroidism (HP) in an adolescent girl
Ann & Robert H Lurie Children’s Hospital of Chicago, Northwestern University, Feinberg School of Medicine, Chicago, USA.
ba0007p201
Vibration therapy improves mobility and has no detrimental impact on bone health in adolescents with mild cerebral palsy independent of daily protocol duration (9 minutes/day vs. 15 minutes/day)
1Liggins Institute, University of Auckland, Auckland, New Zealand; 2Department of Exercise Sciences, University of Auckland, Auckland, New Zealand; 3A Better Start- National Science Challenge, University of Auckland, Auckland, New Zealand; 4Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden.
ba0007p202
Side-alternating vibration training improves mobility and has no detrimental impact on bone health in young children with mild-moderate cerebral palsy
1Liggins Institute, University of Auckland, Auckland, New Zealand; 2Department of Exercise Sciences, University of Auckland, Auckland, New Zealand.
ba0007p203
A qualitative analysis of the burden-of-illness associated with X-linked hypophosphataemia (XLH) in children and adolescents
1MAP BioPharma, Cambridge, UK; 2Birmingham Children’s Hospital and University of Birmingham, Birmingham, UK; 3Royal Manchester Children’s Hospital, Manchester, UK.
ba0007p204
Bone mineral density in surgical hemivertebrae treatment in a prematurely born child − a case study
1Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Serbia; 2University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; 3Special Hospital for Rheumatic Diseases, Novi Sad, Serbia; 4Health Center Bač, Bač, Serbia.
ba0007p205
Robot-assisted exercises in children with cerebral palsy - a case study
1Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Serbia; 2University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; 3University of Novi Sad, Faculty of Technical Sciences, Novi Sad, Serbia.
ba0007p206
Group exercises aimed at poor body posture correction assisted by humanoid robot - A case study
1Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Serbia; 2University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; 3University of Novi Sad, Faculty of Technical Sciences, Novi Sad, Serbia.
ba0007p207
Motor developmental outcomes in 2 babies with very severe osteogenesis imperfecta (type II)
Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK.
ba0007p208
Persistently low trabecular bone mineral density and normal bone strength at the radius over 3 years after simultaneous pancreas kidney transplantation
1Charles University and Motol University Hospital, Praha 5, Czech Republic; 2Institute for Clinical and Experimental Medicine, Praha 4, Czech Republic.
ba0007p209
Value of osteogenesis imperfecta clinical nurse specialists to families and consultants across five UK centres
1Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; 2Bristol Children’s Hospital, Bristol, UK; 3Birmingham Women’s and Children’s Hospital, Birmingham, UK; 4Royal Manchester Children’s Hospital, Manchester, UK; 5Sheffield Children’s, Sheffield, UK; 6Paediatric Osteogenesis Imperfecta National Team (POINT), UK.
ba0007p211
Evaluating the natural history of subcutaneous fat necrosis
The Hospital for Sick Children, Toronto, Canada.
ba0007p215
Hypercalcemia and parathyroid hormone-related peptide expression in a 3 months old boy with Colon Hemangioendothelioma
1Pedro Elizalde Hospital, Buenos Aires, Argentina; 2Universidad Nacional del sur, Bahia Blanca, Argentina.
ba0007p218
Comparison of cell separation methods, using relative expression of specific growth plate zone markers in a pig model
1University Clinic of Pediatrics and Adolescent Medicine, Medical University of Vienna, Währinger Gürtel 18-20 1090, Vienna, Austria; 2Histology and Embryology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria; 3Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
ba0007p219
New perspectives in diagnosis and management of optic neuropathy in fibrous dysplasia: utility of optical coherence tomography and computed tomography measurements
1Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA; 2Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA; 3Craniofacial Anomalies and Regeneration Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.
ba0007p220
Speech and hearing impairment and respiratory complications in a large cohort of patients with Achondroplasia
Evelina London Children’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust, London, UK.
ba0007p221
A preliminary data of a prospective study on Iranian patients with osteogenesis imperfecta
1Biochemistry Department, Pasteur Institute of Iran, Tehran, Iran (Islamic Republic of); 2Molecular Biology Department, Pasteur Institute of Iran, Tehran, Iran; 3Molecular Medicine Department, Pasteur Institute of Iran, Tehran, Iran; 4Mofid Children Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.
ba0007p223
A teenager with recurrent fractures and multiple bone lesions: a diagnostic challenge
Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
ba0007p224
A short girl with severe scoliosis and osteoporosis
Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
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The experience of canakinumab in 2 patients with primary tumor (tumoral) calcinosis
1Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russia; 2Smolensk Children’s Clinical Hospital, Saint-Petersburg, Russia; 3City’s Children’s Hospital#1, Saint-Petersburg, Russia; 4Center of Oncology named after N.N. Petrova of Ministry of Health of Russia, Saint-Petersburg, Russia.
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