Searchable abstracts of presentations at key conferences on calcified tissues

ba0006p133 | (1) | ICCBH2017

Long term treatment with intravenous pamidronate in two children with severe form of juvenile Paget's disease

Verfurth Katja , Hovel Matthias , Schundeln Michael , Bauer Jens , Grasemann Corinna

Presenting problem: Severe forms of juvenile PagetÂ’s Syndrome (JPD) result in extreme bone turnover, necessitating long-term treatment with anti-resorptive drugs to control for bone pain and modeling of bones.Objective: To report clinical and biochemical effects of intravenous treatment with Pamidronate in two children with severe forms of JPD over a time period of 3 and 9 years, respectively. Treatment was commenced at 12 months and 3 years of age,...

ba0003pp410 | Paediatric bone disease | ECTS2014

Bone health in children with hemolytic anemia: does the pathogenesis of hemolysis determine the phenotype of bone alteration?

Schundeln Michael , Goretzki Sarah , Hauffa Pia , Marschke Laura , Wieland Regina , Bauer Jens , Hauffa Berthold , Grasemann Corinna

Introduction: Bone health in patients with sickle cell disease and thalassemia is impaired. These patients feature altered parameters of bone metabolism and bone mineral density.Aim and design: To investigate bone health in patients with hemolytic anemia we conducted a cross-sectional analysis in our Hematology Outpatient Clinic at the ChildrenÂ’s Hospital Essen. The largest subgroups within our cohort are patients with homozygous sickle cell (HBSS) ...

ba0006p205 | (1) | ICCBH2017

Osteopathologies and endocrine late effects in a cohort of 102 juvenile survivors of brain tumors

Schundeln Michael , Fritzemeier Sebastian , Hauffa Pia , Bauer Jens , Hauffa Berthold , Grasemann Corinna

Objectives: Endocrine late effects, including osteopathologies, following diagnosis and treatment of childhood malignancies are studied in adult survivors with alarming results. However, in pediatric patients with brain tumors the risk to develop endocrine late effects is high even during childhood and adolescence.Aim and design: To investigate osteopathologies and endocrine function in juvenile survivors of pediatric brain tumors we conducted a cross-se...