Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p43 | (1) | ICCBH2019

Bone health is compromised in adult patients with childhood-onset autoimmune-polyendocrinopathy-candiadis-ectodermal dystrophy (APECED)

Laakso Saila , Borchers Joonatan , Toiviainen-Salo Sanna , Makitie Outi

Objectives: Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is an autosomal-recessive disorder caused by mutations in the autoimmune regulator gene resulting in insufficient suppression of autoimmunity. The impact of immunological abnormalities and the resulting endocrinopathies on bone health is largely unknown. We performed a comprehensive evaluation of skeletal parameters in a large cohort of adult patients with APECED.Methods:...