Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p250 | Genetics and Epigenetics | ECTS2016

Advancing maternal age at childbirth is associated with less favourable trabecular bone mineral density and tibial cortical bone geometry in young adult male offspring

Verroken Charlotte , Zmierczak Hans , Goemaere Stefan , Kaufman Jean-Marc , Lapauw Bruno

Background: Advancing maternal age at childbirth has been associated with a higher risk of pregnancy complications and with adverse short-term and long-term offspring health outcomes, but little is known about the effects of increasing maternal age on offspring bone acquisition.Objective: To investigate associations of maternal age at childbirth with offspring bone parameters in healthy men at the age of peak bone mass.Methods: We ...

ba0003pp318 | Osteoporosis: treatment | ECTS2014

Preferences of patients and health care professionals for osteoporosis drug treatment: a discrete choice experiment

Hiligsmann Mickael , Dirksen Carmen , Dellaert Benedict , van der Weijden Trudy , Goemaere Stefan , Reginster Jean-Yves , Watson Verity , Boonen Annelies

Objectives: This study aims to evaluate and compare the preferences of patients and health care professionals for osteoporotic drug treatment.Materials and methods: A discrete choice experiment was conducted among patients and health care professionals (general physicians, rheumatologists, and geriatricians) in Belgium. Participants were asked to choose between two hypothetical unlabelled drug treatments (and an opt-out option) that vary in several attri...

ba0004p19 | (1) | ICCBH2015

The role of body composition in the relationship between lifestyle factors and bone parameters of young children

Sioen Isabelle , Solis-Trapala Ivonne , De Schepper Jean , Roggen Inge , Goemaere Stefan , De Henauw Stefaan , Ward Kate

Objectives: Maximising peak bone mass (PBM) during growth is an essential part in the prevention of fractures and osteoporosis later in life. Two of the most important modifiable factors influencing PBM are diet and physical activity (PA). These factors can have either a direct or indirect effect on bone. For example, increasing PA would increase loads directly to the bone or cause muscle changes which would drive changes in bone. This study aimed to assess whether there was a...

ba0005p462 | Other diseases of bone and mineral metabolism | ECTS2016

Secondary bone size deficit in patients with Ehlers–Danlos syndrome

Verroken Charlotte , Calders Patrick , Wandele Inge De , Malfait Fransiska , Zmierczak Hans , Goemaere Stefan , Kaufman Jean-Marc , Lapauw Bruno , Rombaut Lies

Background: Ehlers–Danlos syndrome (EDS) comprises a group of inherited connective tissue disorders, caused by various defects in the biosynthesis or secretion of fibrillar collagens. As collagen represents a major constituent of the bone matrix as well as of tendons and muscle, bone strength in EDS patients might be impaired both via direct and indirect pathways. Although decreased muscle strength, decreased areal bone mineral density (BMD) and increased fracture risk ha...