Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp98 | Bone development/growth and fracture repair | ECTS2013

Identification and characterization of a mesenchymal progenitor cell population involved in fracture healing

Matthews Brya , Grcevic Danka , Wang Liping , Hagiwara Yusuke , Adams Douglas , Kalajzic Ivo

Fracture healing is a multistep process that involves many cell lineages and is still not fully understood. We aimed to identify and characterize population of mesenchymal progenitor cells during its commitment within a fracture callus. To identify and trace cells in periosteum and bone marrow we used αSMA promoter-driven inducible Cre expression (αSMA-CreERT2) combined with a Cre-activated tdTomato reporter (Ai9) to generate αSMACre/Ai9 mice. Tibias, fixed with...