Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p149 | (1) | ICCBH2019

Bone mineral changes in 43 children with osteogenesis imperfecta treated by pamidronate

Kostik Mikhail , Idrisova Rena , Buklaev Dmitry , Bergaliev Arthur , Isupova Eugenia , Chikova Irina , Kalashnikova Olga

Objectives: The purpose of our study was to evaluate the bone mineral accrual in children with osteogenesis imperfecta (OI) treated by pamidronate (PAM).Methods: In retrospective study 43 children with different types of OI were included: 17 boys (39.5%) and 26 girls (60.5%). According to clinical OI, patients were: OI I type -13 (30.2%), OI III type – 24 (55.9%) OI IV type – 4 (9.3%), OI V type 1 (2.3%) and Bruck syndrome 1 (2.3%). The standar...

ba0007p113 | (1) | ICCBH2019

Next-generation sequence and biomarker levels in the patients with early-onset chronic non-bacterial osteomyelitis from North Caucasian region of Russia

Kostik Mikhail , Makhova Maria , Suspitsin Evgeny , Sokolenko Anna , Zorin Vyacheslav , Isupova Eugenia , Magomedova Shamai , Kostik Inna , Takayanagi Hiroshi , Mushkin Alexander , Imyanitov Evgeny

Objectives: Chronic non-bacterial osteomyelitis (CNO) is a heterogenic group of immune-mediated inflammatory bone diseases with unclear pathogenesis. Only a few genes associated with this condition have identified. The aim of the study was to evaluate the spectrum of mutations in genes associated with primary immunodeficiency syndromes (PIDs) and autoinflammatory diseases (AIDs) in the cohort of patients with early-onset CNO from North Caucasus (Dagestan and Chechnya) and asse...