ba0004p145 | (1) | ICCBH2015
Keemink Yvette
, van Brussel Marco
, Sakkers Ralph
, Pruijs Hans
, van Dijk Atty
Background: In pediatric osteogenesis imperfecta (OI), bisphosphonates (BPs) are considered the best treatment option to increase bone density and reduce fracture rate. Pamidronate (PAM) is regarded as standard care for moderate to severe OI. The most recent added BP is intravenous zoledronate (ZOL). ZOL has practical advances over PAM, however research on its efficacy and safety is scarce.Objectives: To investigate the efficacy and safety of treatment w...