Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p67 | (1) | ICCBH2019

Bone health outcomes in children and adolescents with neuromuscular disease

Biggin Andrew , Chua Verene , Wall Christie , Pacey Verity , Gray Kelly , McGee Richard , Poon Myra , Munns Craig

Objectives: To compare and contrast the natural history of osteoporosis and response to zoledronate in children and adolescents with Duchene muscular dystrophy (DMD), spinal muscular atrophy (SMA) or other congenital muscular dystrophies (CMD).Methods: A retrospective medical record review of fracture history, treatment and bone mineral densitometry of children managed at a tertiary centre in Sydney over the last 6 years.Results: A...

ba0007p141 | (1) | ICCBH2019

Hypercalcaemia and osteonecrosis of the jaw in association with denosumab use in the paediatric population

Wall Christie-Lee , Pacey Verity , Gray Kelly , McGee Richard , Fiscaletti Melissa , Poon Myra , Biggin Andrew , Munns Craig

Background: Denosumab (DMAB) is used in adults for the treatment of osteoporosis, giant cell tumour of bone, and cancer metastases. There are little data on paediatric use with clinical decision making reliant on adult data and clinical experience.Presenting problem: We have treated 33 children with DMAB: Perthes disease (n=9), avascular necrosis (n=17), osteoporosis (n=1), aneurysmal bone cyst (n=4) and giant cell tum...