Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p106 | (1) | ICCBH2019

Scoliosis and cardiopulmonary outcomes in adults with osteogenesis imperfecta: a pilot study

Khan Sobiah , Yonko Elizabeth , Carter Erin , Sandhaus Robert , Raggio Cathleen

Objectives: Osteogenesis imperfecta (OI) is a group of rare genetic disorders characterized by osteoporosis, predisposition to fracture, and scoliosis. Recently, however, there has been increased focus on pulmonary insufficiency, as it is the leading cause of mortality in individuals with OI. The primary objective of this study is to determine if reduced pulmonary function in individuals with OI is intrinsic to the underlying connective tissue disorder. Another goal of this st...

ba0007p7 | (1) | ICCBH2019

Bone morphology patterns in children with osteogenesis imperfecta

Citron Kate , Yonko Elizabeth , Khan Sobiah , Carter Erin , Jepsen Karl , Raggio Cathleen

Objectives: The objective of this study is to characterize patterns of bone morphology in children with osteogenesis imperfecta (OI), using measurements of the second metacarpal. A secondary objective is to look for impact of bisphosphonate treatment on bone morphology in this population.Methods: This is an IRB-approved retrospective review of 82 de-identified bone age films (AP hand/wrist) for 42 children with OI (17M, 25F). Measurements (Sectra IDS 7 P...