Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp230 | Osteoporosis: evaluation and imaging | ECTS2014

Combination of spine TBS and clinical risk factors (CRF) can be used to detect women with osteoporotic fracture: a US study

Leib Edward , Lamy Olivier , Winzenrieth Renaud , Hans Didier

BMD alone is not sufficient to predict the fracture risk for an individual. Others parameters, such as microarchitecture play a key role in bone fragility. Several cross-sectional studies have shown the ability of TBS to discriminate fractured from healthy subjects in European populations. The aim of our study is to assess the ability of TBS, evaluated at the lumbar spine, to discriminate subjects with and without fracture in a large white US population....

ba0001pp339 | Osteoporosis: evaluation and imaging | ECTS2013

What is the performance in vertebral fracture discrimination by bone mineral density, micro-architecture estimation, and FRAX in stand-alone, combined or adjusted approaches: the OsteoLaus Study

Lamy Olivier , Krieg Marc-Antoine , Stoll Delphine , Aubry-Rozier Berengere , Metzger Marie , Hans Didier

The aim of the study is to compare the performance of FRAX vs TBS adjusted FRAX using Leslie B et al.1 method to better identify women at high fracture risk. The OsteoLaus cohort (1500 women 50–80 years living in Lausanne, CH) started in 2010. CRF for OP, FRAX, spine and hip BMD, VFA by DXA and TBS were recorded. Sensitivity and specificity in regard to vertebral fracture grade 2 and 3 has been calculated. Net reclassification improvement (NRI) had als...