Searchable abstracts of presentations at key conferences on calcified tissues

ba0001oc3.3 | Osteoporosis pathophysiology and genetics | ECTS2013

Distinct relationships of intramuscular and subcutaneous fat with cortical bone: findings from a cross sectional study of young adult males and females

Deere Kevin , Sayers Adrian , Viljakainen Heli , Lawlor Debbie , Sattar Naveed , Kemp John , Fraser William , Tobias Jon

Introduction: Intracellular fat within muscle and visceral tissue has been suggested to adversely influence bone development.Design: We aimed to compare associations between intramuscular and subcutaneous fat and cortical bone outcomes in young adults, in cross-sectional analyses based on the Avon Longitudinal Study of Parents and Children.Method: Data were collected from a research clinic conducted at 17 years of age. Intramuscula...

ba0007oc1 | (1) | ICCBH2019

Association between age at puberty and bone accrual up to 25 years-old

Elhakeem Ahmed , Frysz Monika , Tilling Kate , Tobias Jon H , Lawlor Debbie A

Objectives: Studies indicate that later puberty is associated with lower bone mineral density (BMD) in childhood. Less is known about effects of puberty timing on long-term bone accrual. We examined association between age at puberty and BMD accrual rate from 10 to 25 years.Methods: This was a prospective birth cohort of healthy largely European people born in southwest England in 1991–1992 and regularly follow-up from birth to mean age 25 years. Ag...

ba0007p163 | (1) | ICCBH2019

Prenatal oligohydramnios is associated with hip shape in adolescent males

Tobias Jon , Frysz Monika , Lawlor Debbie , Aspden Richard , Gregory Jennifer , Ireland Alex

Hip development is influenced by mechanical loading during fetal movement by joint and reaction forces equivalent to several times bodyweight. These forces increase with fetal size and gestation length, and are lower in oligohydramnios and breech presentation which are both risk factors for developmental hip disorders. However, associations between indicators of prenatal mechanical loading and hip shape in later life remain unexplored. We therefore examined associations betwee...

ba0007oc1 | (1) | IMPE2023

Association between age at puberty and bone accrual up to 25 years-old

Elhakeem Ahmed , Frysz Monika , Tilling Kate , Tobias Jon H , Lawlor Debbie A

Objectives: Studies indicate that later puberty is associated with lower bone mineral density (BMD) in childhood. Less is known about effects of puberty timing on long-term bone accrual. We examined association between age at puberty and BMD accrual rate from 10 to 25 years.Methods: This was a prospective birth cohort of healthy largely European people born in southwest England in 1991–1992 and regularly follow-up from birth to mean age 25 years. Ag...

ba0007p163 | (1) | IMPE2023

Prenatal oligohydramnios is associated with hip shape in adolescent males

Tobias Jon , Frysz Monika , Lawlor Debbie , Aspden Richard , Gregory Jennifer , Ireland Alex

Hip development is influenced by mechanical loading during fetal movement by joint and reaction forces equivalent to several times bodyweight. These forces increase with fetal size and gestation length, and are lower in oligohydramnios and breech presentation which are both risk factors for developmental hip disorders. However, associations between indicators of prenatal mechanical loading and hip shape in later life remain unexplored. We therefore examined associations betwee...